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SLC39A5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151235

ZIP5 Antibody: The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ZIP5 (SLC39A5), Polyclonal Antibody
Full Product Name
ZIP5 Antibody
Product Gene Name
Product Synonym Names
ZIP5; ZIP5; LZT-Hs7; ZIP5; Zinc transporter ZIP5; Solute carrier family 39 member 5; ZIP-5; solute carrier family 39 (metal ion transporter), member 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; ZIP5 Antibody is supplied in PBS containing 0.02% sodium azide.
Purity/Purification
ZIP5 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures
Antibody/Peptide Pairs
ZIP5 peptide (MBS152292) is used for blocking the activity of ZIP5 antibody (MBS151235)
OMIM
608730
3D Structure
ModBase 3D Structure for Q6ZMH5
Conjugate
Unconjugated
Immunogen
ZIP5 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIP5.
The immunogen is located within amino acids 330-380 of ZIP5
Positive Control

1) CAT No: MBS151374 - Human Spleen Tissue Lysate
2) CAT No: MBS154333- Human Spleen Tissue Slide
Applications Tested/Suitable for anti-SLC39A5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC-P), Immunofluorescence (IF)
Application Notes for anti-SLC39A5 antibody
ZIP5 antibody can be used for detection of ZIP5 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
Optimal dilutions for each application to be determined by the researcher.

Antibody validated: Western Blot in human samples; Immunohistochemistry in humansamples and Immunofluorescence in human samples. All other applications and speciesnot yet tested.

Western Blot (WB) of anti-SLC39A5 antibody

Western blot analysis of ZIP5 in human spleen tissue lysate with ZIP5 antibody at 1 μg/mL.
Rabbit Anti-SLC39A5 Polyclonal Antibody – Cat# MBS151235

Immunohistochemistry (IHC) of anti-SLC39A5 antibody

Immunohistochemistry of ZIP5 in human spleen tissue with ZIP5 antibody at 2.5 μg/mL.
Rabbit Anti-SLC39A5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151235

Immunofluorescence (IF) of anti-SLC39A5 antibody

Immunofluorescence of ZIP5 in human spleen tissue with ZIP5 antibody at 20 μg/mL.
Rabbit Anti-SLC39A5 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151235

Other Notes

Small volumes of anti-SLC39A5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC39A5 purchase

MBS151235 is an antibody targeting SLC39A5. Also known as ZIP5 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC39A5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc transporter ZIP5
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 5
NCBI Official Symbol
SLC39A5
NCBI Official Synonym Symbols
ZIP5; MYP24; LZT-Hs7
UniProt Protein Name
Zinc transporter ZIP5
UniProt Synonym Protein Names
Solute carrier family 39 member 5; Zrt- and Irt-like protein 5; ZIP-5
Protein Family
UniProt Gene Name
SLC39A5
UniProt Synonym Gene Names
ZIP5; ZIP-5
UniProt Entry Name
S39A5_HUMAN
NCBI Protein Information
zinc transporter ZIP5; zrt- and Irt-like protein 5; solute carrier family 39 member 5; solute carrier family 39 (metal ion transporter), member 5

NCBI Summary for SLC39A5

The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
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UniProt Comments for SLC39A5

SLC39A5: May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status. Belongs to the ZIP transporter (TC 2.A.5) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: basolateral plasma membrane; integral to membrane

Molecular Function: metal ion transmembrane transporter activity

Biological Process: positive regulation of nuclear mRNA splicing, via spliceosome; BMP signaling pathway; eye development; zinc ion transport; transmembrane transport

Disease: Myopia 24, Autosomal Dominant
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SLC39A5 antibody

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