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PEAR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151371

PEAR1 Antibody: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
PEAR1, Polyclonal Antibody
Full Product Name
PEAR1 Antibody
Product Gene Name
Product Synonym Names
PEAR1; JEDI; MEGF12; Platelet endothelial aggregation receptor 1; Multiple epidermal growth factor-like domains protein 12; hPEAR1; platelet endothelial aggregation receptor 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
PEAR1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
PEAR1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
PEAR1 peptide (MBS152683) is used for blocking the activity of PEAR1 antibody (MBS151371)
Molecular Weight
110,666 Da
OMIM
610278
3D Structure
ModBase 3D Structure for Q5VY43
Conjugate
Unconjugated
Immunogen
PEAR1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PEAR1.
Buffer
PEAR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-PEAR1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-PEAR1 antibody
PEAR1 antibody can be used for detection of PEAR1 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-PEAR1 antibody

Western blot analysis of PEAR1 in rat kidney tissue lysate with PEAR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-PEAR1 Polyclonal Antibody – Cat# MBS151371

Immunohistochemistry (IHC) of anti-PEAR1 antibody

Immunohistochemistry of PEAR1 in human kidney tissue with PEAR1 antibody at 2.5 μg/mL.
Rabbit Anti-PEAR1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151371

Immunofluorescence (IF) of anti-PEAR1 antibody

Immunofluorescence of PEAR1 in human kidney tissue with PEAR1 antibody at 20 μg/mL.
Rabbit Anti-PEAR1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151371

Other Notes

Small volumes of anti-PEAR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PEAR1 purchase

MBS151371 is an antibody targeting PEAR1. Also known as PEAR1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PEAR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
platelet endothelial aggregation receptor 1
NCBI Official Synonym Full Names
platelet endothelial aggregation receptor 1
NCBI Official Symbol
PEAR1
NCBI Official Synonym Symbols
JEDI; MEGF12
UniProt Protein Name
Platelet endothelial aggregation receptor 1
UniProt Synonym Protein Names
Multiple epidermal growth factor-like domains protein 12; Multiple EGF-like domains protein 12
UniProt Gene Name
PEAR1
UniProt Synonym Gene Names
MEGF12; hPEAR1; Multiple EGF-like domains protein 12
UniProt Entry Name
PEAR1_HUMAN
NCBI Protein Information
platelet endothelial aggregation receptor 1; hPEAR1; multiple EGF-like-domains 12; multiple EGF-like domains protein 12; multiple epidermal growth factor-like domains protein 12

NCBI Summary for PEAR1

PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008]

UniProt Comments for PEAR1

PEAR1: When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells. Belongs to the MEGF family.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: integral to membrane; phagocytic cup

Biological Process: recognition of apoptotic cell
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-PEAR1 antibody

Organs/Tissues associated with anti-PEAR1 antibody

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