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PERP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151420

PERP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PERP, Polyclonal Antibody
Full Product Name
PERP Antibody
Product Gene Name
Product Synonym Names
PERP; THW; KCP1; PIGPC1; KRTCAP1; 1110017A08Rik; Krtcap1; p53 apoptosis effector related to PMP-22; Keratinocyte-associated protein 1; KCP-1; PERP, TP53 apoptosis effector
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
PERP Antibody is Antibody is DEAE purified.
Preparation and Storage
PERP antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
PERP peptide (MBS152034) is used for blocking the activity of PERP antibody (MBS151420)
Molecular Weight
21 kDa
3D Structure
ModBase 3D Structure for Q9JK95
Conjugate
Unconjugated
Immunogen
PERP antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP, which differ from the mouse sequence by three amino acids.
Buffer
PERP Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-Perp antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-Perp antibody
PERP antibody can be used for detection of PERP by Western blot at 1 mug/mL. A 21 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 mug/mL.

Western Blot (WB) of anti-Perp antibody

Western blot analysis of PERP expression in A431 whole cell lysates in the absence (A) and presence (B) of blocking peptide with PERP antibody at 1 μg/mL.
Rabbit Anti-PERP Polyclonal Antibody – Cat# MBS151420

Immunocytochemistry (IHC) of anti-Perp antibody

Immunocytochemistry of PERP in A431 cells with PERP antibody at 10 μg/mL.
Rabbit Anti-PERP Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS151420

Other Notes

Small volumes of anti-Perp antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Perp purchase

MBS151420 is an antibody targeting Perp. Also known as PERP Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Perp. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
p53 apoptosis effector related to PMP-22
NCBI Official Synonym Full Names
PERP, TP53 apoptosis effector
NCBI Official Symbol
Perp
NCBI Official Synonym Symbols
THW; KCP1; PIGPC1; KRTCAP1; 1110017A08Rik
UniProt Protein Name
p53 apoptosis effector related to PMP-22
UniProt Synonym Protein Names
Keratinocyte-associated protein 1; KCP-1
UniProt Gene Name
Perp
UniProt Synonym Gene Names
Krtcap1; KCP-1
UniProt Entry Name
PERP_MOUSE
NCBI Protein Information
p53 apoptosis effector related to PMP-22; KCP-1; p53 apoptosis-associated target; keratinocyte-associated protein 1; p53 apoptosis effector related to Pmp22

UniProt Comments for Perp

PERP: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. Belongs to the TMEM47 family.

Protein type: Membrane protein, multi-pass; Mitochondrial; Cell adhesion; Membrane protein, integral

Cellular Component: Golgi apparatus; mitochondrion; membrane; integral to plasma membrane; integral to membrane; plasma membrane; cell junction

Biological Process: heterotypic cell-cell adhesion; apoptosis; positive regulation of proteolysis; cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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