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C1QTNF3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151520

CTRP3 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of… More details

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Product Overview

Online Datasheet in PDF
Product Name
CTRP3 (C1QTNF3), Polyclonal Antibody
Full Product Name
CTRP3 Antibody
Product Gene Name
anti-C1QTNF3 antibody
Product Synonym Names
CTRP3; CORS; CORCS; CTRP3; CORS26; C1ATNF3; CORS-26; UNQ753/PRO1484; Complement C1q tumor necrosis factor-related protein 3; Collagenous repeat-containing sequence 26 kDa protein; C1q and tumor necrosis factor related protein 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
CTRP3 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Multiple isoforms of CTRP3 are known to exist. CTRP3 antibody is predicted to not recognize other members of the CTRP protein family
Preparation and Storage
CTRP3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
CTRP3 peptide (MBS152457) is used for blocking the activity of CTRP3 antibody (MBS151520)
Molecular Weight
Predicted: 27kD
Observed: 30 kD (Post-modyfication: 1 N-linked glycosylation)
OMIM
612045
3D Structure
ModBase 3D Structure for Q9BXJ4
Conjugate
Unconjugated
Immunogen
Anti-CTRP3 antibody (MBS151520) was raised against a peptide corresponding to 16 amino acids near the center of human CTRP3. The immunogen is located within amino acids 90-140 of CTRP3.
Buffer
CTRP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-C1QTNF3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-C1QTNF3 antibody
CTRP3 antibody can be used for the detection of CTRP3 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 2 ug/mL. For immunofluorescence start at 10 ug/mL.

Western Blot (WB) of anti-C1QTNF3 antibody

Western blot analysis of CTRP3 in mouse heart cell lysate with CTRP3 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
Rabbit Anti-C1QTNF3 Polyclonal Antibody – Cat# MBS151520

Western Blot (WB) of anti-C1QTNF3 antibody

Western Blot Validation in Human and Mouse Cell Lines Loading: 15 ug of lysates per lane. Antibodies: CTRP3, MBS151520 (1 ug/mL), 1h incubation at RT in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
Rabbit Anti-C1QTNF3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS151520

Western Blot (WB) of anti-C1QTNF3 antibody

Western Blot Validation with Recombinant Protein Loading: 30 ng of human CTRP3 recombinant protein per lane. Antibodies: CTRP3, MBS151520 (2 ug/mL), 1h incubation at RT in 5% NFDM/TBST.Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
Rabbit Anti-C1QTNF3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS151520

Western Blot (WB) of anti-C1QTNF3 antibody

Western Blot Validation in Mouse and Rat Tissue Lysates Loading: 15 ug of lysates per lane. Antibodies: CTRP3, MBS151520 (1 ug/mL), 1h incubation at RT in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
Rabbit Anti-C1QTNF3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS151520

Western Blot (WB) of anti-C1QTNF3 antibody

Western Blot Validation in Mouse Heart Tissue Lysate in the (A) absence and (B) presence of blocking peptide Loading: 15 ug of lysates per lane. Antibodies: CTRP3, MBS151520 (1 ug/mL), 1h incubation at RT in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
Rabbit Anti-C1QTNF3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS151520

Immunohistochemistry (IHC) of anti-C1QTNF3 antibody

Immunohistochemistry of CTRP3 in mouse heart tissue with CTRP3 antibody at 2 μg/mL.
Rabbit Anti-C1QTNF3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151520

Immunofluorescence (IF) of anti-C1QTNF3 antibody

Immunofluorescence of CTRP3 in Mouse Heart tissue with CTRP3 antibody at 10 μg/mL.
Rabbit Anti-C1QTNF3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151520

Other Notes

Small volumes of anti-C1QTNF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C1QTNF3 purchase

MBS151520 is an antibody targeting C1QTNF3. Also known as CTRP3 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for C1QTNF3. It may not necessarily be applicable to this product.

NCBI GI #
62739183
NCBI GeneID
114899
NCBI Accession #
NP_852100
UniProt Primary Accession #
Q9BXJ4
UniProt Secondary Accession #
Q0VAN4; Q542Y2; Q6MZN1; Q96KY1
UniProt Related Accession #
Q9BXJ4
GenBank Nucleotide #
NM_181435.5
NCBI Official Full Name
complement C1q tumor necrosis factor-related protein 3 isoform b
NCBI Official Synonym Full Names
C1q and tumor necrosis factor related protein 3
NCBI Official Symbol
C1QTNF3
NCBI Official Synonym Symbols
CORS; CORCS; CTRP3; CORS26; C1ATNF3; CORS-26
UniProt Protein Name
Complement C1q tumor necrosis factor-related protein 3
UniProt Synonym Protein Names
Collagenous repeat-containing sequence 26 kDa protein; CORS26; Secretory protein CORS26
Protein Family
Complement C1q tumor necrosis factor-related protein
UniProt Gene Name
C1QTNF3
UniProt Synonym Gene Names
CTRP3; CORS26
UniProt Entry Name
C1QT3_HUMAN
NCBI Protein Information
complement C1q tumor necrosis factor-related protein 3; cartonectin; secretory protein CORS26; collagenous repeat-containing sequence of 26-kDa; collagenous repeat-containing sequence 26 kDa protein

UniProt Comments for C1QTNF3

C1QTNF3: 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5p13

Cellular Component: extracellular space; collagen; membrane

Molecular Function: protein binding

Biological Process: fat cell differentiation; negative regulation of gluconeogenesis; negative regulation of inflammatory response; negative regulation of NF-kappaB import into nucleus; positive regulation of cytokine secretion
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Research Articles on C1QTNF3

1. Patients with acute coronary syndrome or stable angina pectoris had significantly lower circulating CTRP-3 concentrations compared to controls.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-C1QTNF3 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >20 publications with C1QTNF3 and Necrosis
 Inflammation Antibodies  >7 publications with C1QTNF3 and Inflammation
 Insulin Resistance Antibodies  >4 publications with C1QTNF3 and Insulin Resistance
 Disease Models, Animal Antibodies  >2 publications with C1QTNF3 and Disease Models, Animal
 Immune System Diseases Antibodies  >1 publications with C1QTNF3 and Immune System Diseases
 Ovarian Diseases Antibodies  >1 publications with C1QTNF3 and Ovarian Diseases
 Intestinal Neoplasms Antibodies  >1 publications with C1QTNF3 and Intestinal Neoplasms
 Kidney Diseases Antibodies  >1 publications with C1QTNF3 and Kidney Diseases
 Fibrosis Antibodies  >1 publications with C1QTNF3 and Fibrosis
 Hyperplasia Antibodies  >1 publications with C1QTNF3 and Hyperplasia

Organs/Tissues associated with anti-C1QTNF3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >11 publications with C1QTNF3 and Blood
 Connective Tissue Antibodies  >7 publications with C1QTNF3 and Connective Tissue
 Muscle Antibodies  >2 publications with C1QTNF3 and Muscle
 Eye Antibodies  >1 publications with C1QTNF3 and Eye
 Kidney Antibodies  >1 publications with C1QTNF3 and Kidney
 Heart Antibodies  >1 publications with C1QTNF3 and Heart
 Intestine Antibodies  >1 publications with C1QTNF3 and Intestine
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