• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

KREMEN1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153356

KREMEN1 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KREMEN1, Polyclonal Antibody
Full Product Name
KREMEN1 Antibody
Product Gene Name
Product Synonym Names
KREMEN1; KRM1; KREMEN; KRM1; Kremen protein 1; Dickkopf receptor; kringle containing transmembrane protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
KREMEN1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Three isoforms of KREMEN1 exists as a result of alternative splicing event.
Preparation and Storage
KREMEN1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
KREMEN1 peptide (MBS153761) is used for blocking the activity of KREMEN1 antibody (MBS153356)
Molecular Weight
54 kDa
OMIM
609898
3D Structure
ModBase 3D Structure for Q96MU8
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1.
Buffer
KREMEN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-KREMEN1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-KREMEN1 antibody
KREMEN1 antibody can be used for detection of KREMEN1 by Western blot at 0.5 - 1 mug/mL.

Western Blot (WB) of anti-KREMEN1 antibody

Western blot analysis of KREMEN1 in rat small intestine tissue lysate with KREMEN1 antibody at (A) 0.125 and (B) 0.25 μg/mL
Rabbit Anti-KREMEN1 Polyclonal Antibody – Cat# MBS153356

Immunohistochemistry (IHC) of anti-KREMEN1 antibody

Immunohistochemistry of KREMEN1 in human small intestine tissue with KREMEN1 antibody at 5 μg/ml.
Rabbit Anti-KREMEN1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153356

Immunofluorescence (IF) of anti-KREMEN1 antibody

Immunofluorescence of KREMEN1 in human small intestine tissue with KREMEN1 antibody at 20 μg/ml.
Rabbit Anti-KREMEN1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153356

Other Notes

Small volumes of anti-KREMEN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KREMEN1 purchase

MBS153356 is an antibody targeting KREMEN1. Also known as KREMEN1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KREMEN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kremen protein 1 isoform 2
NCBI Official Synonym Full Names
kringle containing transmembrane protein 1
NCBI Official Symbol
KREMEN1
NCBI Official Synonym Symbols
KRM1; KREMEN
UniProt Protein Name
Kremen protein 1
UniProt Synonym Protein Names
Dickkopf receptor; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose
Protein Family
UniProt Gene Name
KREMEN1
UniProt Synonym Gene Names
KREMEN; KRM1
UniProt Entry Name
KREM1_HUMAN
NCBI Protein Information
kremen protein 1; dickkopf receptor; kringle-coding gene marking the eye and the nose; kringle domain-containing transmembrane protein 1; kringle-containing protein marking the eye and the nose

NCBI Summary for KREMEN1

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for KREMEN1

KREMEN1: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q12.1

Cellular Component: membrane; integral to membrane

Molecular Function: protein binding

Biological Process: Wnt receptor signaling pathway; cell communication
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000