Rabbit Anti-DIRAS3 Polyclonal Antibody – Cat# MBS153530

Western blot analysis of DIRAS3 in human testis tissue lysate with DIRAS3 antibody at 1 μg/ml.

DIRAS3 Antibody – Rabbit Polyclonal

Name: DIRAS3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS153530
Price: 530 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153530

DIRAS3 is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with mono-allelic expression of the paternal allele, which is associated with growth… More details

$530 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DIRAS3, Polyclonal Antibody

Full Product Name

DIRAS3 Antibody

Product Gene Name

anti-DIRAS3 antibody

Product Synonym Names

DIRAS family GTP-binding RAS-like 3; ARHI; NOEY2 ; DIRAS family, GTP-binding RAS-like 3

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

DIRAS3 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL (lot specific)

Specificity

DIRAS3 antibody is human specific.

Preparation and Storage

DIRAS3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Antibody/Peptide Pairs

DIRAS3 peptide (MBS153764) is used for blocking the activity of DIRAS3 antibody (MBS153530)

Molecular Weight

Predicted: 25 kDa

Observed: 24 kDa

OMIM

605193

3D Structure

ModBase 3D Structure for O95661

Conjugate

Unconjugated

Immunogen

DIRAS3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DIRAS3.

Buffer

DIRAS3 antibody is supplied in PBS containing 0.02% sodium azide.

Applications Tested/Suitable for anti-DIRAS3 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-DIRAS3 antibody

DIRAS3 antibody can be used for detection of DIRAS3 by Western blot at 1 - 2 mug/ml.

Other Notes

Small volumes of anti-DIRAS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DIRAS3 purchase

MBS153530 is an antibody targeting DIRAS3. Also known as DIRAS3 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DIRAS3. It may not necessarily be applicable to this product.

NCBI GI #

4757772

NCBI GeneID

9077

NCBI Accession #

NP_004666

UniProt Primary Accession #

O95661

UniProt Secondary Accession #

B3KMP3

UniProt Related Accession #

O95661

GenBank Nucleotide #

NM_004675.2

NCBI Official Full Name

GTP-binding protein Di-Ras3

NCBI Official Synonym Full Names

DIRAS family, GTP-binding RAS-like 3

NCBI Official Symbol

DIRAS3

NCBI Official Synonym Symbols

ARHI; NOEY2

UniProt Protein Name

GTP-binding protein Di-Ras3

UniProt Synonym Protein Names

Distinct subgroup of the Ras family member 3; Rho-related GTP-binding protein RhoI

Protein Family

GTP-binding protein

UniProt Gene Name

DIRAS3

UniProt Synonym Gene Names

ARHI; NOEY2; RHOI

UniProt Entry Name

DIRA3_HUMAN

NCBI Protein Information

GTP-binding protein Di-Ras3; ras homolog gene family, member I; rho-related GTP-binding protein RhoI; distinct subgroup of the Ras family member 3

NCBI Summary for DIRAS3

This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. [provided by RefSeq, Oct 2010]

UniProt Comments for DIRAS3

DIRAS3: a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. [provided by RefSeq, Oct 2010]

Protein type: G protein, monomeric, di-Ras; G protein, monomeric; G protein

Chromosomal Location of Human Ortholog: 1p31

Cellular Component: plasma membrane

Molecular Function: GTPase activity; protein binding; GTP binding

Biological Process: genetic imprinting; small GTPase mediated signal transduction; regulation of cyclin-dependent protein kinase activity

Research Articles on DIRAS3

1. ARHI acts as a tumor suppressor gene in MDA-MB-231 cells and, although trichostatin A+5-aza-2'-deoxycytidine can block the cells at different cell cycle phase, the antitumor effect is ARHI-dependent.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DIRAS3 antibody

Reference Product	PubMed Publications
STAT3 antibody	>8 publications with DIRAS3 and STAT3
CDKN1B antibody	>4 publications with DIRAS3 and CDKN1B
PRL antibody	>1 publications with DIRAS3 and PRL

Diseases associated with anti-DIRAS3 antibody

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>3 publications with DIRAS3 and Liver Diseases
Prostatic Neoplasms Antibodies	>2 publications with DIRAS3 and Prostatic Neoplasms
Abnormalities, Multiple Antibodies	>2 publications with DIRAS3 and Abnormalities, Multiple
Cell Transformation, Neoplastic Antibodies	>2 publications with DIRAS3 and Cell Transformation, Neoplastic
Lung Neoplasms Antibodies	>1 publications with DIRAS3 and Lung Neoplasms
Precancerous Conditions Antibodies	>1 publications with DIRAS3 and Precancerous Conditions
Hyperplasia Antibodies	>1 publications with DIRAS3 and Hyperplasia
Respiratory Tract Diseases Antibodies	>1 publications with DIRAS3 and Respiratory Tract Diseases
Disease Models, Animal Antibodies	>1 publications with DIRAS3 and Disease Models, Animal
Diabetes Mellitus Antibodies	>1 publications with DIRAS3 and Diabetes Mellitus

Organs/Tissues associated with anti-DIRAS3 antibody

Organ/Tissue Name	Pubmed Publications
Ovary Antibodies	>7 publications with DIRAS3 and Ovary
Brain Antibodies	>4 publications with DIRAS3 and Brain
Thyroid Antibodies	>3 publications with DIRAS3 and Thyroid
Vascular Antibodies	>3 publications with DIRAS3 and Vascular
Placenta Antibodies	>3 publications with DIRAS3 and Placenta
Embryonic Tissue Antibodies	>2 publications with DIRAS3 and Embryonic Tissue
Pancreas Antibodies	>2 publications with DIRAS3 and Pancreas
Lung Antibodies	>2 publications with DIRAS3 and Lung
Heart Antibodies	>2 publications with DIRAS3 and Heart
Intestine Antibodies	>1 publications with DIRAS3 and Intestine