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TIAF Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153556

TIAF Antibody: TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TIAF, Polyclonal Antibody
Full Product Name
TIAF Antibody
Product Gene Name
Product Synonym Names
TIAF; MAJN; SPR210; TGFB1-induced anti-apoptotic factor 1; 12 kDa TGF-beta-1-induced antiapoptotic factor; TGFB1-induced anti-apoptotic factor 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
TIAF Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Two alternatively spliced transcript variants encoding different isoforms have been identified.
Preparation and Storage
TIAF antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
TIAF peptide (MBS153909) is used for blocking the activity of TIAF antibody (MBS153556)
Molecular Weight
Predicted: 13 kDa

Observed: 14 kDa
OMIM
609517
3D Structure
ModBase 3D Structure for O95411
Conjugate
Unconjugated
Immunogen
TIAF antibody was raised against a 16 amino acid peptide near the amino terminus of human TIAF.
Buffer
TIAF Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-TIAF antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-TIAF antibody
TIAF Antibody can be used for detection of TIAF by Western blot at 1 mug/mL.

Western Blot (WB) of anti-TIAF antibody

Western blot analysis of TIAF in K562 cell lysate with TIAF antibody at 1 μg/mL.
Rabbit Anti-TIAF Polyclonal Antibody – Cat# MBS153556

Immunocytochemistry (IHC) of anti-TIAF antibody

Immunocytochemistry of TIAF in K562 cells with TIAF antibody at 2.5 μg/ml.
Rabbit Anti-TIAF Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS153556

Other Notes

Small volumes of anti-TIAF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TIAF purchase

MBS153556 is an antibody targeting TIAF. Also known as TIAF Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TIAF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TGFB1-induced anti-apoptotic factor 1
NCBI Official Synonym Full Names
TGFB1-induced anti-apoptotic factor 1
NCBI Official Symbol
TIAF1
NCBI Official Synonym Symbols
MAJN; SPR210
UniProt Protein Name
TGFB1-induced anti-apoptotic factor 1
UniProt Synonym Protein Names
12 kDa TGF-beta-1-induced antiapoptotic factor
UniProt Gene Name
TIAF1
UniProt Entry Name
TIAF1_HUMAN
NCBI Protein Information
TGFB1-induced anti-apoptotic factor 1; TGF-beta-1-induced antiapoptotic factor 1; molecule associated with Jak-3 N-terminal; 12 kDa TGF-beta-1-induced antiapoptotic factor

UniProt Comments for TIAF

TIAF1: Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: nucleus

Biological Process: I-kappaB kinase/NF-kappaB cascade; apoptosis; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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