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AMIGO1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153560

The amphoterin-induced gene and ORF (AMIGO1) protein is a brain-enriched, glycosylated transmembrane immunoglobulin (Ig) superfamily protein with six extracellular leucine-rich repeats (LRRs) and one Ig-like domain. It and the related proteins AMIGO2 and… More details

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Product Overview

Online Datasheet in PDF
Product Name
AMIGO1, Polyclonal Antibody
Full Product Name
AMIGO1 Antibody
Product Gene Name
anti-AMIGO1 antibody
Product Synonym Names
AMIGO1; ALI2; AMIGO; AMIGO-1; ALI2; KIAA1163; Amphoterin-induced protein 1; adhesion molecule with Ig-like domain 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
AMIGO1 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
AMIGO1 antibody is human, mouse, and rat reactive. AMIGO1 antibody is predicted to not cross-react with AMIGO2 or AMIGO3.
Preparation and Storage
AMIGO1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
AMIGO1 peptide (MBS154143) is used for blocking the activity of AMIGO1 antibody (MBS153560)
Molecular Weight
Predicted: 54 kDa

Observed: 55 kDa
OMIM
615689
3D Structure
ModBase 3D Structure for Q86WK6
Conjugate
Unconjugated
Immunogen
AMIGO1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AMIGO1
Buffer
AMIGO1 antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-AMIGO1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-AMIGO1 antibody
AMIGO1 antibody can be used for detection of AMIGO1 by Western blot at 1 - 2 mug/ml. Antibody can also be used for Immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-AMIGO1 antibody

Western blot analysis of AMIGO1 in HeLa cell lysate with AMIGO1 antibody at (A) 1 and (B) 2 μg/ml.
Rabbit Anti-AMIGO1 Polyclonal Antibody – Cat# MBS153560

Immunohistochemistry (IHC) of anti-AMIGO1 antibody

Immunohistochemistry of AMIGO1 in human brain tissue with AMIGO1 antibody at 5 μg/mL.
Rabbit Anti-AMIGO1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153560

Immunofluorescence (IF) of anti-AMIGO1 antibody

Immunofluorescence of AMIGO1 in human brain tissue with AMIGO1 antibody at 20 μg/mL.
Rabbit Anti-AMIGO1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153560

Other Notes

Small volumes of anti-AMIGO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMIGO1 purchase

MBS153560 is an antibody targeting AMIGO1. Also known as AMIGO1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AMIGO1. It may not necessarily be applicable to this product.

NCBI GI #
153791466
NCBI GeneID
57463
NCBI Accession #
NP_065754
UniProt Primary Accession #
Q86WK6
UniProt Secondary Accession #
Q8IW71; Q9ULQ7; B4DIM3
UniProt Related Accession #
Q86WK6
GenBank Nucleotide #
NM_020703.2
NCBI Official Full Name
amphoterin-induced protein 1
NCBI Official Synonym Full Names
adhesion molecule with Ig-like domain 1
NCBI Official Symbol
AMIGO1
NCBI Official Synonym Symbols
ALI2; AMIGO; AMIGO-1
UniProt Protein Name
Amphoterin-induced protein 1
UniProt Synonym Protein Names
AMIGO-1; Alivin-2
Protein Family
Amphoterin-induced protein
UniProt Gene Name
AMIGO1
UniProt Entry Name
AMGO1_HUMAN
NCBI Protein Information
amphoterin-induced protein 1; AMIGO1; alivin-2; amphoterin-induced gene and ORF

UniProt Comments for AMIGO1

AMIGO1: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Belongs to the immunoglobulin superfamily. AMIGO family.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: axon; plasma membrane; integral to membrane

Biological Process: myelination; heterophilic cell adhesion; axonogenesis; axonal fasciculation; positive regulation of axonogenesis; brain development; homophilic cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AMIGO1 antibody

 Reference Product  PubMed Publications
 HMGB1 antibody  >4 publications with AMIGO1 and HMGB1
 AMIGO2 antibody  >1 publications with AMIGO1 and AMIGO2
 AMIGO3 antibody  >1 publications with AMIGO1 and AMIGO3

Diseases associated with anti-AMIGO1 antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >1 publications with AMIGO1 and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with AMIGO1 and Nervous System Diseases

Organs/Tissues associated with anti-AMIGO1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with AMIGO1 and Brain
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