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Beclin 2 (BECN1P1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153642

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells (1,2). Beclin 2 is a mammalian specific homolog of the autophagy protein… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Beclin 2 (BECN1P1), Polyclonal Antibody
Full Product Name
Beclin 2 Antibody
Product Gene Name
Product Synonym Names
BECN2; BECN1L1; Beclin-1-like protein 1; Beclin 1 autophagy related pseudogene 1; BECN1P1; beclin 1, autophagy related, pseudogene 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Beclin 2 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Beclin 2 antibody is human specific. At least two isoforms of Beclin 2 are known to exist; this antibody will only detect the longer isoform. Beclin 2 antibody is predicted to not cross-react with Beclin 1.
Preparation and Storage
Beclin 2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Molecular Weight
Predicted: 47 kDa

Observed: 55 kDa
OMIM
615687
3D Structure
ModBase 3D Structure for A8MW95
Conjugate
Unconjugated
Immunogen
Beclin 2 antibody was raised against a 16 amino acid peptide near the amino terminus of human Beclin 2.
Buffer
Beclin 2 antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-BECN1P1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-BECN1P1 antibody
Beclin 2 antibody can be used for detection of Beclin 2 by Western blot at 1 - 2 mug/ml. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-BECN1P1 antibody

Western blot analysis of Beclin 2 in Jurkat cell lysate with Beclin 2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-BECN1P1 Polyclonal Antibody – Cat# MBS153642

Other Notes

Small volumes of anti-BECN1P1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BECN1P1 purchase

MBS153642 is an antibody targeting BECN1P1. Also known as Beclin 2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BECN1P1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
beclin-2
NCBI Official Synonym Full Names
beclin 1, autophagy related, pseudogene 1
NCBI Official Symbol
BECN1P1
NCBI Official Synonym Symbols
BECN2; BECN1L1
UniProt Protein Name
Beclin-2
UniProt Synonym Protein Names
Beclin-1 autophagy-related pseudogene 1; Beclin-1-like protein 1
Protein Family
UniProt Gene Name
BECN1P1
UniProt Entry Name
BECN2_HUMAN
NCBI Protein Information
beclin-2; Beclin-1-like protein 1; beclin-1 autophagy-related pseudogene 1

UniProt Comments for BECN1P1

BECN1L1: May play a role in autophagy and antiviral host defense (Potential). Belongs to the beclin family.

Chromosomal Location of Human Ortholog: 1q43

Cellular Component: cytoplasm

Molecular Function: protein binding

Biological Process: endosome to lysosome transport; autophagy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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