Gata Binding Protein 2 (GATA2) ELISA Kit for Human

Name: Human GATA2 ELISA Kit; Gata Binding Protein 2; MyBioSource
Brand: MyBioSource
SKU: MBS015400
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS015400

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of GATA2 (hereafter termed "analyte") in undiluted… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Gata Binding Protein 2 (GATA2), ELISA Kit

Full Product Name

Human Gata Binding Protein 2 ELISA Kit

Product Gene Name

GATA2 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Detection Range

3.12ng/ml-100ng/ml

Sensitivity

1.0ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

50,500 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (128198265..128212030, complement). Location: 3q21.3

OMIM

137295

3D Structure

ModBase 3D Structure for P23769

Other Notes

Small volumes of GATA2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GATA2 purchase

MBS015400 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Gata Binding Protein 2 (GATA2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GATA2. The ELISA analytical biochemical technique of the MBS015400 kit is based on GATA2 antibody-GATA2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GATA2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GATA2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GATA2. It may not necessarily be applicable to this product.

NCBI GI #

30410878

NCBI GeneID

2624

NCBI Accession #

AAH51272.1

UniProt Primary Accession #

P23769

UniProt Secondary Accession #

Q53YE0; Q96BH0; Q96BH8; Q9BUJ6; D3DNB3

UniProt Related Accession #

P23769

NCBI Official Full Name

GATA2 protein

NCBI Official Synonym Full Names

GATA binding protein 2

NCBI Official Symbol

GATA2

NCBI Official Synonym Symbols

DCML; NFE1B; MONOMAC

UniProt Protein Name

Endothelial transcription factor GATA-2

UniProt Synonym Protein Names

GATA-binding protein 2

Protein Family

Endothelial transcription factor

UniProt Gene Name

GATA2

UniProt Entry Name

GATA2_HUMAN

NCBI Protein Information

endothelial transcription factor GATA-2

NCBI Summary for GATA2

This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

UniProt Comments for GATA2

GATA2: Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'. Endothelial cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: nucleoplasm; protein complex

Molecular Function: protein binding; zinc ion binding; chromatin binding; transcription factor binding; transcription factor activity

Biological Process: embryonic placenta development; inner ear morphogenesis; transcription, DNA-dependent; somatic stem cell maintenance; positive regulation of erythrocyte differentiation; cell maturation; regulation of histone acetylation; negative regulation of transcription from RNA polymerase II promoter; cell fate determination; negative regulation of fat cell differentiation; phagocytosis; positive regulation of angiogenesis; cell differentiation in hindbrain; negative regulation of macrophage differentiation; commitment of a neuronal cell to a specific type of neuron in the forebrain; ventral spinal cord interneuron differentiation; pituitary gland development; homeostasis of number of cells within a tissue; positive regulation of phagocytosis; negative regulation of Notch signaling pathway; positive regulation of megakaryocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; urogenital system development; central nervous system neuron development

Disease: Lymphedema, Primary, With Myelodysplasia; Immunodeficiency 21; Myelodysplastic Syndrome

Research Articles on GATA2

1. GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GATA2 elisa kit

Reference Product	PubMed Publications
JUN elisa kit	>71 publications with GATA2 and JUN
TAL1 elisa kit	>57 publications with GATA2 and TAL1
LMO2 elisa kit	>35 publications with GATA2 and LMO2
ZFPM1 elisa kit	>14 publications with GATA2 and ZFPM1
ZFPM2 elisa kit	>5 publications with GATA2 and ZFPM2
POU1F1 elisa kit	>2 publications with GATA2 and POU1F1
HDAC5 elisa kit	>1 publications with GATA2 and HDAC5
HDAC3 elisa kit	>1 publications with GATA2 and HDAC3
EDN1 elisa kit	>1 publications with GATA2 and EDN1

Pathways associated with GATA2 elisa kit

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
HIF-1-alpha Transcription Factor Network Pathway antibodies	HIF-1-alpha Transcription Factor Network Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
IL-3 Signaling Pathway antibodies	IL-3 Signaling Pathway Diagram
Regulation Of Androgen Receptor Activity Pathway antibodies	Regulation Of Androgen Receptor Activity Pathway Diagram
SIDS Susceptibility Pathways antibodies	SIDS Susceptibility Pathways Diagram
Signaling Events Mediated By HDAC Class I Pathway antibodies	Signaling Events Mediated By HDAC Class I Pathway Diagram
Signaling Events Mediated By HDAC Class II Pathway antibodies	Signaling Events Mediated By HDAC Class II Pathway Diagram

Diseases associated with GATA2 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>126 publications with GATA2 and Neoplasms
Leukemia, Myeloid, Acute Antibodies	>56 publications with GATA2 and Leukemia, Myeloid, Acute
Myelodysplastic Syndromes Antibodies	>17 publications with GATA2 and Myelodysplastic Syndromes
Inflammation Antibodies	>14 publications with GATA2 and Inflammation
Cardiovascular Diseases Antibodies	>14 publications with GATA2 and Cardiovascular Diseases
Brain Diseases Antibodies	>12 publications with GATA2 and Brain Diseases
Necrosis Antibodies	>10 publications with GATA2 and Necrosis
Drug Toxicity Antibodies	>8 publications with GATA2 and Drug Toxicity
Neoplasms, Experimental Antibodies	>8 publications with GATA2 and Neoplasms, Experimental
Hypertrophy Antibodies	>7 publications with GATA2 and Hypertrophy

Organs/Tissues associated with GATA2 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>261 publications with GATA2 and Blood
Embryonic Tissue Antibodies	>87 publications with GATA2 and Embryonic Tissue
Vascular Antibodies	>77 publications with GATA2 and Vascular
Bone Marrow Antibodies	>76 publications with GATA2 and Bone Marrow
Brain Antibodies	>52 publications with GATA2 and Brain
Heart Antibodies	>27 publications with GATA2 and Heart
Placenta Antibodies	>23 publications with GATA2 and Placenta
Kidney Antibodies	>22 publications with GATA2 and Kidney
Muscle Antibodies	>22 publications with GATA2 and Muscle
Lung Antibodies	>14 publications with GATA2 and Lung