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LANCL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS154355

MBS154355 is an antibody targeting LANCL2. Also known as LANCL2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LANCL2, Polyclonal Antibody
Full Product Name
LANCL2 Antibody
Product Gene Name
Product Synonym Names
LanC lantibiotic synthetase component C-like 2, GPR69B, LanC-like protein 2, TASP, Testis-specific adriamycin sensitivity protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid; Supplied in PBS containing 0.02% sodium azide.
Purity/Purification
Affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
LANCL2 antibody is human, mouse and rat reactive.
Preparation and Storage
LANCL2 antobody can be stored at 4°C for three months and -20°C , stable for up to 1 year.
Antibody/Peptide Pairs
LANCL1 peptide (MBS154396) is used for blocking the activity of LANCL2 antibody (MBS154355)
OMIM
612919
3D Structure
ModBase 3D Structure for Q9NS86
Immunogen
LANCL2 antibody was raised against a 16 amino acid peptide from near the amino terminus of human LANCL2.
The immunogen is located within amino acids 30-80 of LANCL2.

Product Categories/Family for anti-LANCL2 antibody

Applications Tested/Suitable for anti-LANCL2 antibody
ELISA, Western Blot (WB), Immunohistochemistry - Paraffin (IHC-P)
Application Notes for anti-LANCL2 antibody
Optimal dilutions for each application to be determined by the researcher.
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guidline for product use. This product is for research use only.

Western Blot (WB) of anti-LANCL2 antibody

Western blot analysis of LANCL2 in human brain tissue lysate with LANCL2 antibody at 1 μg/ml.
Rabbit Anti-LANCL2 Polyclonal Antibody – Cat# MBS154355

Immunohistochemistry (IHC) of anti-LANCL2 antibody

Immunohistochemistry of LANCL2 in mouse brain tissue with LANCL2 antibody at 5 μg/mL.
Rabbit Anti-LANCL2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS154355

Product References and Citations for anti-LANCL2 antibody

Mayer H, Pongratz M, and Prohaska R. Molecular cloning, characterization, and tissue-specific expression of human LANCL2, a novel member of the LanC-like protein family. DNA Seq. 2001; 12:161-6. Sturla L, Fresia C, Guida L, et al. Binding of abscisic acid to human LANCL2. Biochem. Biophys. Res. Commun. 2011; 415:390-5. Landlinger C, Salzer U, and Prohaska R. Myristoylation of human LanC-like protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin. Biochim. Biophys. Acta. 2006; 1758:1759-67. Zeng M, van der Donk WA, Chen J. Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt. Mol. Biol. Cell 2014; 25:3954-61.

Other Notes

Small volumes of anti-LANCL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LANCL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lanC-like protein 2
NCBI Official Synonym Full Names
LanC like 2
NCBI Official Symbol
LANCL2
NCBI Official Synonym Symbols
TASP; GPR69B
UniProt Protein Name
LanC-like protein 2
UniProt Synonym Protein Names
Testis-specific adriamycin sensitivity protein
Protein Family
UniProt Gene Name
LANCL2
UniProt Synonym Gene Names
GPR69B; TASP
UniProt Entry Name
LANC2_HUMAN
NCBI Protein Information
lanC-like protein 2

UniProt Comments for LANCL2

LANCL2: Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. Belongs to the LanC-like protein family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 7q31.1-q31.33

Cellular Component: cortical actin cytoskeleton; cytoplasm; cytosol; nucleus; plasma membrane

Molecular Function: ATP binding; catalytic activity; GTP binding; phosphatidylinositol 3-phosphate binding; phosphatidylinositol-5-phosphate binding; protein binding

Biological Process: metabolic process; negative regulation of transcription, DNA-dependent; positive regulation of abscisic acid mediated signaling
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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