Protein Tyrosine Phosphatase Receptor Type O (PTPRO) ELISA Kit for Rat

Name: Rat PTPRO ELISA Kit; Protein Tyrosine Phosphatase Receptor Type O; MyBioSource
Brand: MyBioSource
SKU: MBS160171
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS160171

MBS160171 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protein Tyrosine Phosphatase Receptor Type O (PTPRO) ELISA Kit target analytes in biological samples. The concentration… More details

$445 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Protein Tyrosine Phosphatase Receptor Type O (PTPRO), ELISA Kit

Full Product Name

Rat Protein Tyrosine Phosphatase Receptor Type O (PTPRO) ELISA Kit

Product Gene Name

PTPRO elisa kit

Species Reactivity

Rat

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

134,941 Da

3D Structure

ModBase 3D Structure for Q16827

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PTPRO elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPRO. It may not necessarily be applicable to this product.

NCBI GI #

23271167

NCBI GeneID

5800

NCBI Accession #

AAH35960.1

UniProt Primary Accession #

Q16827

UniProt Secondary Accession #

Q13101; Q8IYG3; Q9UBF0; Q9UBT5; A0AV39

UniProt Related Accession #

Q16827

NCBI Official Full Name

PTPRO protein

NCBI Official Synonym Full Names

protein tyrosine phosphatase, receptor type O

NCBI Official Symbol

PTPRO

NCBI Official Synonym Symbols

NPHS6; PTPU2; GLEPP1; PTP-OC; PTP-U2; PTPROT; R-PTP-O

UniProt Protein Name

Receptor-type tyrosine-protein phosphatase O

UniProt Synonym Protein Names

Glomerular epithelial protein 1; Protein tyrosine phosphatase U2; PTP-U2; PTPase U2

Protein Family

Receptor-type tyrosine-protein phosphatase

UniProt Gene Name

PTPRO

UniProt Synonym Gene Names

GLEPP1; PTPU2; R-PTP-O; PTP-U2; PTPase U2

NCBI Protein Information

receptor-type tyrosine-protein phosphatase O

NCBI Summary for PTPRO

This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]

UniProt Comments for PTPRO

Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function ().

Research Articles on PTPRO

1. the present study demonstrated that PTPRO inhibits tumor growth in vitro and in vivo, indicating the tumor suppressive function of PTPRO in LSCC. This study highlights PTPRO as an epigenetically silenced gene, and a candidate tumor-suppressor of LSCC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTPRO elisa kit

Reference Product	PubMed Publications
PTPRU elisa kit	>7 publications with PTPRO and PTPRU
SYNPO elisa kit	>5 publications with PTPRO and SYNPO
NPHS2 elisa kit	>4 publications with PTPRO and NPHS2
ACTN4 elisa kit	>1 publications with PTPRO and ACTN4
CD2AP elisa kit	>1 publications with PTPRO and CD2AP
KIT elisa kit	>1 publications with PTPRO and KIT

Pathways associated with PTPRO elisa kit

Products by Pathway	Pathway Diagram
Signaling Events Mediated By Stem Cell Factor Receptor (c-Kit) Pathway antibodies	Signaling Events Mediated By Stem Cell Factor Receptor (c-Kit) Pathway Diagram

Diseases associated with PTPRO elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>19 publications with PTPRO and Neoplasms
Kidney Diseases Antibodies	>16 publications with PTPRO and Kidney Diseases
Proteinuria Antibodies	>12 publications with PTPRO and Proteinuria
Disease Models, Animal Antibodies	>6 publications with PTPRO and Disease Models, Animal
Carcinoma, Hepatocellular Antibodies	>3 publications with PTPRO and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>2 publications with PTPRO and Liver Diseases
Adenocarcinoma Antibodies	>2 publications with PTPRO and Adenocarcinoma
Edema Antibodies	>2 publications with PTPRO and Edema
Breast Neoplasms Antibodies	>2 publications with PTPRO and Breast Neoplasms
Liver Neoplasms Antibodies	>2 publications with PTPRO and Liver Neoplasms

Organs/Tissues associated with PTPRO elisa kit

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>31 publications with PTPRO and Kidney
Brain Antibodies	>14 publications with PTPRO and Brain
Blood Antibodies	>12 publications with PTPRO and Blood
Nerve Antibodies	>9 publications with PTPRO and Nerve
Lung Antibodies	>5 publications with PTPRO and Lung
Bone Marrow Antibodies	>5 publications with PTPRO and Bone Marrow
Eye Antibodies	>4 publications with PTPRO and Eye
Spleen Antibodies	>3 publications with PTPRO and Spleen
Muscle Antibodies	>2 publications with PTPRO and Muscle
Connective Tissue Antibodies	>1 publications with PTPRO and Connective Tissue