Leukotriene B4 Receptor 1, LTB4R (LTB4R) ELISA Kit for Rat

Name: Rat LTB4R ELISA Kit; Leukotriene B4 Receptor 1, LTB4R; MyBioSource
Brand: MyBioSource
SKU: MBS165845
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS165845

Intended Uses: This sandwich kit is for the accurate quantitative detection of Rat Leukocyte Common Antigen (also known as LCA/CD45) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.Principle of the Assay: This kit is an… More details

$445 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Leukotriene B4 receptor 1, LTB4R, ELISA Kit

Full Product Name

Rat Leukotriene B4 receptor 1, LTB4R ELISA Kit

Product Gene Name

LTB4R elisa kit

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Serum, Plasma, Cell Culture Supernates, Cell Lysates, Tissue Homogenates

Detection Range

0.05ng/ml-15ng/ml

Sensitivity

0.021ng/ml

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Inter-assay Precision

Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision. CV(%) = SD/mean x 100. Inter-Assay: CV<10%

Intra-assay Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision. Intra-Assay: CV<8%

Molecular Weight

37,557 Da

3D Structure

ModBase 3D Structure for Q15722

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LTB4R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LTB4R purchase

MBS165845 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Leukotriene B4 receptor 1, LTB4R, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LTB4R. The ELISA analytical biochemical technique of the MBS165845 kit is based on LTB4R antibody-LTB4R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LTB4R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LTB4R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for LTB4R. It may not necessarily be applicable to this product.

NCBI GI #

31881792

NCBI GeneID

1241

NCBI Accession #

NP_858043.1

UniProt Primary Accession #

Q15722

UniProt Secondary Accession #

Q13305; Q53XV5; Q92641; Q9BSU5

UniProt Related Accession #

Q15722

GenBank Nucleotide #

NM_181657.3

NCBI Official Full Name

leukotriene B4 receptor 1

NCBI Official Synonym Full Names

leukotriene B4 receptor

NCBI Official Symbol

LTB4R

NCBI Official Synonym Symbols

BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1

UniProt Protein Name

Leukotriene B4 receptor 1

UniProt Synonym Protein Names

Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7

Protein Family

Leukotriene B4 receptor

UniProt Gene Name

LTB4R

UniProt Synonym Gene Names

BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7; LTB4-R 1; LTB4-R1; P2Y7

NCBI Protein Information

leukotriene B4 receptor 1

UniProt Comments for LTB4R

Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

Research Articles on LTB4R

1. fact, leukotriene B4 (LTB4) is an eicosanoid lipid derivative of arachidonic acid, which primarily binds itself to the high-affinity G protein-coupled receptor BLT1. BLT1 plays an indispensable role in atherosclerosis. Hence, the BLT1 antagonist might have a therapeutic role in treating atherosclerosis. [review]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LTB4R elisa kit

Reference Product	PubMed Publications
ADRBK1 elisa kit	>1 publications with LTB4R and ADRBK1
CCK elisa kit	>1 publications with LTB4R and CCK

Pathways associated with LTB4R elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Eicosanoid Ligand-binding Receptors Pathway antibodies	Eicosanoid Ligand-binding Receptors Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Leukotriene Receptors Pathway antibodies	Leukotriene Receptors Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with LTB4R elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>31 publications with LTB4R and Inflammation
Asthma Antibodies	>15 publications with LTB4R and Asthma
Neoplasms Antibodies	>14 publications with LTB4R and Neoplasms
Necrosis Antibodies	>8 publications with LTB4R and Necrosis
Pancreatic Neoplasms Antibodies	>2 publications with LTB4R and Pancreatic Neoplasms
Leukemia, Myeloid Antibodies	>2 publications with LTB4R and Leukemia, Myeloid
Fibrosis Antibodies	>2 publications with LTB4R and Fibrosis
Disease Models, Animal Antibodies	>2 publications with LTB4R and Disease Models, Animal
Neoplasms, Experimental Antibodies	>2 publications with LTB4R and Neoplasms, Experimental
Leukemia Antibodies	>2 publications with LTB4R and Leukemia

Organs/Tissues associated with LTB4R elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>42 publications with LTB4R and Blood
Lung Antibodies	>13 publications with LTB4R and Lung
Skin Antibodies	>5 publications with LTB4R and Skin
Bone Marrow Antibodies	>5 publications with LTB4R and Bone Marrow
Kidney Antibodies	>3 publications with LTB4R and Kidney
Spleen Antibodies	>2 publications with LTB4R and Spleen
Eye Antibodies	>1 publications with LTB4R and Eye
Ovary Antibodies	>1 publications with LTB4R and Ovary
Brain Antibodies	>1 publications with LTB4R and Brain
Uterus Antibodies	>1 publications with LTB4R and Uterus