Porcine IL4R/CD124 ELISA Kit – Cat# MBS166018

Interleukin 4 Receptor, IL4R/CD124 (IL4R/CD124) ELISA Kit for Porcine

Name: Porcine IL4R/CD124 ELISA Kit; Interleukin 4 Receptor, IL4R/CD124; MyBioSource
Brand: MyBioSource
SKU: MBS166018
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS166018

MBS166018 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 4 receptor, IL4R/CD124, ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$520 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Interleukin 4 receptor, IL4R/CD124, ELISA Kit

Full Product Name

Porcine Interleukin 4 receptor, IL4R/CD124 ELISA Kit

Product Gene Name

IL4R/CD124 elisa kit

Species Reactivity

Porcine

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

25,553 Da

3D Structure

ModBase 3D Structure for P24394

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IL4R/CD124 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL4R/CD124. It may not necessarily be applicable to this product.

NCBI GI #

33834

NCBI GeneID

3566

NCBI Accession #

CAA36672.1

UniProt Primary Accession #

P24394

UniProt Secondary Accession #

Q96P01; Q9H181; Q9H182; Q9H183; Q9H184; Q9H185; Q9H186; Q9H187; B4E076; B9EKU8; H3BSY5

UniProt Related Accession #

P24394

NCBI Official Full Name

interleukin 4 receptor

NCBI Official Synonym Full Names

interleukin 4 receptor

NCBI Official Symbol

IL4R

NCBI Official Synonym Symbols

CD124; IL4RA; IL-4RA

UniProt Protein Name

Interleukin-4 receptor subunit alpha

UniProt Synonym Protein Names

CD_antigen: CD124

UniProt Gene Name

IL4R

UniProt Synonym Gene Names

IL4RA; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; sIL4Ralpha/prot; IL4-BP

NCBI Protein Information

interleukin-4 receptor subunit alpha

NCBI Summary for IL4R/CD124

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]

UniProt Comments for IL4R/CD124

Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

Research Articles on IL4R/CD124

1. IL-4R plays an important role in regulating hepatocellular carcinoma (HCC)cell survival and metastasis, and regulates the activity of the JAK1/STAT6 and JNK/ERK1/2 signaling pathways. We therefore suggest that IL-4/IL-4R may be a new therapeutic target for HCC

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IL4R/CD124 elisa kit

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
IL-4 Signaling Pathway antibodies	IL-4 Signaling Pathway Diagram
IL4-mediated Signaling Events Pathway antibodies	IL4-mediated Signaling Events Pathway Diagram
Inflammatory Response Pathway antibodies	Inflammatory Response Pathway Diagram
Inflammatory Bowel Disease (IBD) Pathway antibodies	Inflammatory Bowel Disease (IBD) Pathway Diagram
Inflammatory Bowel Disease (IBD) Pathway antibodies	Inflammatory Bowel Disease (IBD) Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram

Diseases associated with IL4R/CD124 elisa kit

Disease Name	Pubmed Publications
Asthma Antibodies	>45 publications with IL4R/CD124 and Asthma
Inflammation Antibodies	>35 publications with IL4R/CD124 and Inflammation
Nervous System Diseases Antibodies	>22 publications with IL4R/CD124 and Nervous System Diseases
Necrosis Antibodies	>17 publications with IL4R/CD124 and Necrosis
Cardiovascular Diseases Antibodies	>10 publications with IL4R/CD124 and Cardiovascular Diseases
Drug-Related Side Effects and Adverse Reactions Antibodies	>8 publications with IL4R/CD124 and Drug-Related Side Effects and Adverse Reactions
Kidney Diseases Antibodies	>6 publications with IL4R/CD124 and Kidney Diseases
Leukemia Antibodies	>6 publications with IL4R/CD124 and Leukemia
HIV Infections Antibodies	>6 publications with IL4R/CD124 and HIV Infections
Breast Neoplasms Antibodies	>5 publications with IL4R/CD124 and Breast Neoplasms

Organs/Tissues associated with IL4R/CD124 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>75 publications with IL4R/CD124 and Blood
Skin Antibodies	>13 publications with IL4R/CD124 and Skin
Brain Antibodies	>9 publications with IL4R/CD124 and Brain
Bone Antibodies	>7 publications with IL4R/CD124 and Bone
Vascular Antibodies	>7 publications with IL4R/CD124 and Vascular
Lung Antibodies	>7 publications with IL4R/CD124 and Lung
Kidney Antibodies	>6 publications with IL4R/CD124 and Kidney
Lymph Node Antibodies	>3 publications with IL4R/CD124 and Lymph Node
Heart Antibodies	>3 publications with IL4R/CD124 and Heart
Bone Marrow Antibodies	>3 publications with IL4R/CD124 and Bone Marrow