Human DEFb114 ELISA Kit – Cat# MBS166235

Defensin Beta 114 (DEFb114) ELISA Kit for Human

Name: Human DEFb114 ELISA Kit; Defensin Beta 114; MyBioSource
Brand: MyBioSource
SKU: MBS166235
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS166235

MBS166235 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Defensin Beta 114 (DEFb114) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Defensin Beta 114 (DEFb114), ELISA Kit

Full Product Name

Human Defensin Beta 114 (DEFb114) ELISA Kit

Product Gene Name

DEFb114 elisa kit

Species Reactivity

Human

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

8,318 Da

3D Structure

ModBase 3D Structure for Q30KQ6

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DEFb114 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DEFb114. It may not necessarily be applicable to this product.

NCBI GI #

22252912

NCBI GeneID

245928

NCBI Accession #

AAM93912.1

UniProt Primary Accession #

Q30KQ6

UniProt Secondary Accession #

Q8NES9

UniProt Related Accession #

Q30KQ6

NCBI Official Full Name

defensin beta 114, partial

NCBI Official Synonym Full Names

defensin beta 114

NCBI Official Symbol

DEFB114

NCBI Official Synonym Symbols

DEFB14; DEFB-14

UniProt Protein Name

Beta-defensin 114

UniProt Synonym Protein Names

Beta-defensin 14; DEFB-14; Defensin, beta 114

Protein Family

Beta-defensin

UniProt Gene Name

DEFB114

UniProt Synonym Gene Names

DEFB14; DEFB-14

NCBI Protein Information

beta-defensin 114

NCBI Summary for DEFb114

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. The protein encoded by this gene is a beta-defensin with antimicrobial activity against E. coli, S. aureus, and C. albicans. The encoded protein also binds and neutralizes lipopolysaccharide (LPS), a factor involved in inflammatory diseases and male reproductive issues. [provided by RefSeq, Nov 2014]

UniProt Comments for DEFb114

Has a salt-sensitive antimicrobial activity against Gram-negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.

Research Articles on DEFb114

1. Human beta-defensin 114 regulates lipopolysaccharide (LPS)-mediated inflammation and protects sperm from motility loss. It also has antimicrobial activity against E. coli, S. aureus, and C. albicans.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DEFb114 elisa kit

Products by Pathway	Pathway Diagram
Beta Defensins Pathway antibodies	Beta Defensins Pathway Diagram
Defensins Pathway antibodies	Defensins Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with DEFb114 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>1 publications with DEFb114 and Inflammation