Human HSD17B8 ELISA Kit – Cat# MBS166676

Estradiol 17-Beta-Dehydrogenase 8, HSD17B8 (HSD17B8) ELISA Kit for Human

Name: Human HSD17B8 ELISA Kit; Estradiol 17-Beta-Dehydrogenase 8, HSD17B8; MyBioSource
Brand: MyBioSource
SKU: MBS166676
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS166676

MBS166676 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Estradiol 17-beta-dehydrogenase 8, HSD17B8, ELISA Kit target analytes in biological samples. The concentration gradients of the… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Estradiol 17-beta-dehydrogenase 8, HSD17B8, ELISA Kit

Full Product Name

Human Estradiol 17-beta-dehydrogenase 8, HSD17B8 ELISA Kit

Product Gene Name

HSD17B8 elisa kit

Species Reactivity

Human

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

26,974 Da

3D Structure

ModBase 3D Structure for Q92506

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HSD17B8 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HSD17B8. It may not necessarily be applicable to this product.

NCBI GI #

15277342

NCBI GeneID

7923

NCBI Accession #

NP_055049.1

UniProt Primary Accession #

Q92506

UniProt Secondary Accession #

Q5STP7; Q9UIQ1; A6NLX7

UniProt Related Accession #

Q92506

GenBank Nucleotide #

NM_014234.4

NCBI Official Full Name

estradiol 17-beta-dehydrogenase 8

NCBI Official Synonym Full Names

hydroxysteroid 17-beta dehydrogenase 8

NCBI Official Symbol

HSD17B8

NCBI Official Synonym Symbols

KE6; FABG; HKE6; FABGL; RING2; H2-KE6; SDR30C1; D6S2245E; dJ1033B10.9

UniProt Protein Name

Estradiol 17-beta-dehydrogenase 8

UniProt Synonym Protein Names

17-beta-hydroxysteroid dehydrogenase 8

Protein Family

Estradiol 17 beta-dehydrogenase

UniProt Gene Name

HSD17B8

UniProt Synonym Gene Names

FABGL; HKE6; RING2; SDR30C1; 17-beta-HSD 8; KAR alpha subunit1 PublicationManual assertion based on opinion iniRef.12; Ke-6

NCBI Protein Information

estradiol 17-beta-dehydrogenase 8

NCBI Summary for HSD17B8

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for HSD17B8

NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone (PubMed:17978863). The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508).

Research Articles on HSD17B8

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HSD17B8 elisa kit

Products by Pathway	Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Steroid Hormone Biosynthesis Pathway antibodies	Steroid Hormone Biosynthesis Pathway Diagram
Steroid Hormone Biosynthesis Pathway antibodies	Steroid Hormone Biosynthesis Pathway Diagram

Diseases associated with HSD17B8 elisa kit

Disease Name	Pubmed Publications
Neoplasm Metastasis Antibodies	>1 publications with HSD17B8 and Neoplasm Metastasis

Organs/Tissues associated with HSD17B8 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with HSD17B8 and Liver
Placenta Antibodies	>2 publications with HSD17B8 and Placenta
Testis Antibodies	>2 publications with HSD17B8 and Testis
Brain Antibodies	>2 publications with HSD17B8 and Brain
Lung Antibodies	>2 publications with HSD17B8 and Lung
Kidney Antibodies	>2 publications with HSD17B8 and Kidney
Heart Antibodies	>1 publications with HSD17B8 and Heart
Lymph Antibodies	>1 publications with HSD17B8 and Lymph
Pancreas Antibodies	>1 publications with HSD17B8 and Pancreas
Lymph Node Antibodies	>1 publications with HSD17B8 and Lymph Node