Nitrotyrosine Antibody – Rabbit Polyclonal

• Affinity purified antibodies at 1 mg/mL
• Suitable for Western blot or ELISA applications

The modification of tyrosine residues in proteins to 3-nitrotyrosine by peroxynitrite (Figure 1) or other potential nitrating agents has been detected in biological systems that are subject to oxidative stress. Detection of nitrotyrosine-containing proteins has been reported in many human and animal diseases or cellular models of disease. While all tyrosine residues in proteins may theoretically be targets for nitration, presumably the efficiency of tyrosine nitration is dependent on various biological conditions such as the local production and concentration of the reactive species, the existence and availability of antioxidants and scavengers, the accumulation of inflammatory cell and the presence of pro-inflammatory cytokines, as well as the proximity and compartmentation of these components.

Small volumes of anti-Nitrotyrosine antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS168890 is an antibody targeting Nitrotyrosine. Also known as Rabbit Anti-Nitrotyrosine Polyclonal Antibody. Reactive in Any. Host: Rabbit.