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MIG Antibody – Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177721

Description: Rabbit IgG polyclonal antibody for C-X-C motif chemokine 9(CXCL9) detection. Tested with WB, ELISA in Human.Background: MIG, also known as CXCL9, is a T-cell chemoattractant inducible by gamma interferon that is a member of the CXC chemokine… More details

$210 / 0.01 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MIG, Polyclonal Antibody
Full Product Name
Anti-MIG Antibody
Product Gene Name
anti-MIG antibody
Product Synonym Names
C-X-C motif chemokine 9; C-X-C motif chemokine 9; chemokine (C-X-C motif) ligand 9; CMK; crg-10; CXCL9; CXCL9_HUMAN; Gamma-interferon-induced monokine; Humig; MIG; monokine induced by gamma interferon; Monokine induced by interferon-gamma; SCYB9; Small inducible cytokine B9; small inducible cytokine subfamily B member 9; Small-inducible cytokine B9; chemokine (C-X-C motif) ligand 9
Clonality
Polyclonal
Species Reactivity
Human
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen Affinity Purified
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
14,019 Da
OMIM
601704
3D Structure
ModBase 3D Structure for Q07325
Immunogen
E Coli-derived human MIG recombinant protein (Position: T23-T125). Human MIG shares 68.2% amino acid (aa) sequence identity with mouse MIG.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-MIG antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-MIG antibody
ELISA Concentration: 0.1-0.5ug/ml
Western Blot Concentration: 0.1-0.5ug/ml

Western Blot (WB) of anti-MIG antibody

Anti- CXCL9 Picoband antibody, MBS177721, Western blotting
All lanes: Anti CXCL9 (MBS177721) at 0.5ug/ml
Lane 1: Human Placenta Tissue Lysate at 50ug
Lane 2: A431 Whole Cell Lysate at 40ug
Lane 3: HELA Whole Cell Lysate at 40ug
Predicted bind size: 14KD
Observed bind size: 19KD
Anti-MIG Polyclonal Antibody – Cat# MBS177721

Product References and Citations for anti-MIG antibody

1. Lee HH, Farber JM (1996). "Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine "mini-cluster"". Cytogenet. Cell Genet. 74 (4): 255-8. 2. O'Donovan N, Galvin M, Morgan JG (1999). "Physical mapping of the CXC chemokine locus on human chromosome 4". Cytogenet. Cell Genet. 84 (1-2): 39-42. 3. Tensen CP, Flier J, Van Der Raaij-Helmer EM, Sampat-Sardjoepersad S, Van Der Schors RC, Leurs R, Scheper RJ, Boorsma DM, Willemze R (1999). "Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)". J. Invest. Dermatol. 112 (5): 716-22.

Other Notes

Small volumes of anti-MIG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIG purchase

MBS177721 is an antibody targeting MIG. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for MIG. It may not necessarily be applicable to this product.

NCBI GI #
4505187
NCBI GeneID
4283
NCBI Accession #
NP_002407.1
UniProt Primary Accession #
Q07325
UniProt Secondary Accession #
Q503B4
UniProt Related Accession #
Q07325
GenBank Nucleotide #
NM_002416.2
NCBI Official Full Name
C-X-C motif chemokine 9
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 9
NCBI Official Symbol
CXCL9
NCBI Official Synonym Symbols
CMK; MIG; Humig; SCYB9; crg-10
UniProt Protein Name
C-X-C motif chemokine 9
UniProt Synonym Protein Names
Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; HuMIG; MIG; Small-inducible cytokine B9
Protein Family
Migration and invasion enhancer
UniProt Gene Name
CXCL9
UniProt Synonym Gene Names
CMK; MIG; SCYB9; HuMIG; MIG
UniProt Entry Name
CXCL9_HUMAN
NCBI Protein Information
C-X-C motif chemokine 9

NCBI Summary for MIG

This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014]

UniProt Comments for MIG

CXCL9: Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: external side of plasma membrane; extracellular region; extracellular space

Molecular Function: chemokine activity; CXCR3 chemokine receptor binding; cytokine activity; protein binding

Biological Process: cell-cell signaling; cellular defense response; chemotaxis; defense response; defense response to virus; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; positive regulation of cAMP metabolic process; positive regulation of leukocyte chemotaxis; positive regulation of myoblast differentiation; positive regulation of release of sequestered calcium ion into cytosol; regulation of cell proliferation; response to lipopolysaccharide; signal transduction
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Research Articles on MIG

1. Knock-down of CD44 resulted in an upregulation of mRNA expression of the chemokines CXCL9 and CXCL12, as well as their receptors CXCR3 and CXCR4.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MIG antibody

 Reference Product  PubMed Publications
 CXCR3 antibody  >545 publications with MIG and CXCR3
 CCL5 antibody  >282 publications with MIG and CCL5
 CCR5 antibody  >96 publications with MIG and CCR5
 CXCL12 antibody  >87 publications with MIG and CXCL12
 CCL20 antibody  >68 publications with MIG and CCL20
 CCL21 antibody  >37 publications with MIG and CCL21
 CCR3 antibody  >32 publications with MIG and CCR3
 IL8 antibody  >29 publications with MIG and IL8
 CXCL6 antibody  >17 publications with MIG and CXCL6
 PF4 antibody  >6 publications with MIG and PF4

Pathways associated with anti-MIG antibody

 Products by Pathway  Pathway Diagram
 CXCR3-mediated Signaling Events Pathway antibodies  CXCR3-mediated Signaling Events Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram

Diseases associated with anti-MIG antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >484 publications with MIG and Inflammation
 Necrosis Antibodies  >242 publications with MIG and Necrosis
 Disease Models, Animal Antibodies  >185 publications with MIG and Disease Models, Animal
 Nervous System Diseases Antibodies  >141 publications with MIG and Nervous System Diseases
 Lung Diseases Antibodies  >140 publications with MIG and Lung Diseases
 Liver Diseases Antibodies  >105 publications with MIG and Liver Diseases
 Carcinoma Antibodies  >81 publications with MIG and Carcinoma
 Cardiovascular Diseases Antibodies  >75 publications with MIG and Cardiovascular Diseases
 Fibrosis Antibodies  >71 publications with MIG and Fibrosis
 Hypersensitivity Antibodies  >65 publications with MIG and Hypersensitivity

Organs/Tissues associated with anti-MIG antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >937 publications with MIG and Blood
 Lung Antibodies  >186 publications with MIG and Lung
 Skin Antibodies  >156 publications with MIG and Skin
 Liver Antibodies  >145 publications with MIG and Liver
 Brain Antibodies  >109 publications with MIG and Brain
 Lymph Node Antibodies  >100 publications with MIG and Lymph Node
 Spleen Antibodies  >86 publications with MIG and Spleen
 Kidney Antibodies  >86 publications with MIG and Kidney
 Heart Antibodies  >62 publications with MIG and Heart
 Intestine Antibodies  >43 publications with MIG and Intestine
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