Anti-KIF3A Polyclonal Antibody – Cat# MBS177783

Anti- KIF3A Picoband antibody, MBS177783, Western blotting
All lanes: Anti KIF3A (MBS177783) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: Rat Testis Tissue Lysate at 50ug
Lane 3: Mouse Brain Tissue Lysate at 50ug
Lane 4: Mouse Testis Tissue Lysate at 50ug
Lane 5: MCF-7 Whole Cell Lysate at 40ug
Predicted bind size: 80KD
Observed bind size: 80KD

KIF3A Antibody – Polyclonal

Name: KIF3A Antibody; Polyclonal; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS177783
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177783

Description: Rabbit IgG polyclonal antibody for Kinesin-like protein KIF3A(KIF3A) detection. Tested with WB in Human;Mouse;Rat.Background: Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene. KIF3A is one subunit of the… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KIF3A, Polyclonal Antibody

Full Product Name

Anti-KIF3A Antibody

Product Gene Name

anti-KIF3A antibody

Product Synonym Names

Kinesin-like protein KIF3A; KIF 3; KIF 3A; KIF3; Kif3a; KIF3A_HUMAN; Kifl; Kinesin family member 3A; Kinesin family protein 3; Kinesin family protein 3A; Kinesin like protein KIF 3A; Kinesin like protein KIF3A; Kinesin-like protein KIF3A; Kns3; Microtubule plus end directed kinesin motor 3A; Microtubule plus end-directed kinesin motor 3A; kinesin family member 3A

Clonality

Polyclonal

Species Reactivity

Human, Mouse, Rat

Form/Format

Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purity/Purification

Immunogen Affinity Purified

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

80,041 Da

OMIM

604683

3D Structure

ModBase 3D Structure for Q9Y496

Immunogen

E Coli-derived human KIF3A recombinant protein (Position: D485-Q699). Human KIF3A shares 97.7% amino acid (aa) sequence identity with mouse KIF3A.

Ig Type

Rabbit IgG

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-KIF3A antibody

Western Blot (WB)

Application Notes for anti-KIF3A antibody

Western Blot Concentration: 0.1-0.5ug/ml

Product References and Citations for anti-KIF3A antibody

1. Cole DG, Chinn SW, Wedaman KP, Hall K, Vuong T, Scholey JM (November 1993). "Novel heterotrimeric kinesin-related protein purified from sea urchin eggs". Nature 366 (6452): 268-70. 2. Nonaka S, Tanaka Y, Okada Y, Takeda S, Harada A, Kanai Y, Kido M, Hirokawa N (December 1998). "Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein". Cell 95 (6): 829-37. 3. Rosenbaum JL, Witman GB (November 2002). "Intraflagellar transport". Nat. Rev. Mol. Cell Biol. 3 (11): 813-25.

Other Notes

Small volumes of anti-KIF3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIF3A purchase

MBS177783 is an antibody targeting KIF3A. Reactive in Human, Mouse, Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for KIF3A. It may not necessarily be applicable to this product.

NCBI GI #

663853723

NCBI GeneID

11127

NCBI Accession #

NP_001287720.1

UniProt Primary Accession #

Q9Y496

UniProt Secondary Accession #

Q59EN1; Q86XE9; Q9Y6V4; A8MSW9

UniProt Related Accession #

Q9Y496

GenBank Nucleotide #

NM_001300791.1

NCBI Official Full Name

kinesin-like protein KIF3A isoform 1

NCBI Official Synonym Full Names

kinesin family member 3A

NCBI Official Symbol

KIF3A

NCBI Official Synonym Symbols

FLA10; KLP-20

UniProt Protein Name

Kinesin-like protein KIF3A

UniProt Synonym Protein Names

Microtubule plus end-directed kinesin motor 3A

Protein Family

Kinesin-like protein

UniProt Gene Name

KIF3A

UniProt Synonym Gene Names

KIF3

UniProt Entry Name

KIF3A_HUMAN

NCBI Protein Information

kinesin-like protein KIF3A

UniProt Comments for KIF3A

KIF3A: Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Heterodimer of KIF3A and KIF3B. Interacts with PIFO/C1orf88. Interacts with CLN3. Belongs to the kinesin-like protein family. Kinesin II subfamily.

Protein type: Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: centrosome; cytosol; kinesin II complex; microtubule cytoskeleton; spindle microtubule

Molecular Function: ATP binding; microtubule binding; plus-end-directed microtubule motor activity; protein binding; spectrin binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; cilium biogenesis; metabolic process; microtubule-based movement; neurogenesis; organelle organization and biogenesis; retrograde vesicle-mediated transport, Golgi to ER

Research Articles on KIF3A

1. These data suggest that GLI interactions with KIF3A-KIF3B-KAP3 complexes are essential for proper GLI transcriptional activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KIF3A antibody

Reference Product	PubMed Publications
KIF3B antibody	>37 publications with KIF3A and KIF3B
KIF3C antibody	>13 publications with KIF3A and KIF3C
GLI3 antibody	>10 publications with KIF3A and GLI3
GLI2 antibody	>10 publications with KIF3A and GLI2
KIFAP3 antibody	>7 publications with KIF3A and KIFAP3
PPP1R15A antibody	>1 publications with KIF3A and PPP1R15A

Pathways associated with anti-KIF3A antibody

Products by Pathway	Pathway Diagram
Activation Of SMO Pathway antibodies	Activation Of SMO Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
COPI-dependent Golgi-to-ER Retrograde Traffic Pathway antibodies	COPI-dependent Golgi-to-ER Retrograde Traffic Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Golgi-to-ER Retrograde Transport Pathway antibodies	Golgi-to-ER Retrograde Transport Pathway Diagram
Hedgehog 'off' State Pathway antibodies	Hedgehog 'off' State Pathway Diagram
Hedgehog 'on' State Pathway antibodies	Hedgehog 'on' State Pathway Diagram
Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies	Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram

Diseases associated with anti-KIF3A antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>21 publications with KIF3A and Kidney Diseases
Craniofacial Abnormalities Antibodies	>4 publications with KIF3A and Craniofacial Abnormalities
Carcinoma Antibodies	>4 publications with KIF3A and Carcinoma
Bone Diseases, Developmental Antibodies	>4 publications with KIF3A and Bone Diseases, Developmental
Asthma Antibodies	>4 publications with KIF3A and Asthma
Kidney Neoplasms Antibodies	>3 publications with KIF3A and Kidney Neoplasms
Acute Kidney Injury Antibodies	>3 publications with KIF3A and Acute Kidney Injury
Fibrosis Antibodies	>2 publications with KIF3A and Fibrosis
Polydactyly Antibodies	>2 publications with KIF3A and Polydactyly
Adenocarcinoma Antibodies	>2 publications with KIF3A and Adenocarcinoma

Organs/Tissues associated with anti-KIF3A antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>50 publications with KIF3A and Brain
Kidney Antibodies	>39 publications with KIF3A and Kidney
Nerve Antibodies	>32 publications with KIF3A and Nerve
Eye Antibodies	>24 publications with KIF3A and Eye
Bone Antibodies	>20 publications with KIF3A and Bone
Embryonic Tissue Antibodies	>16 publications with KIF3A and Embryonic Tissue
Muscle Antibodies	>10 publications with KIF3A and Muscle
Blood Antibodies	>10 publications with KIF3A and Blood
Testis Antibodies	>10 publications with KIF3A and Testis
Skin Antibodies	>9 publications with KIF3A and Skin