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AMIGO-1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS190914

The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
AMIGO-1, Monoclonal Antibody
Full Product Name
AMIGO-1 Monoclonal Antibody
Product Gene Name
Product Synonym Names
Anti-AMIGO-1
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Specificity
This antibody recognizes human, mouse and rat AMIGO-1. It does not cross-react with AMIGO-2 or AMIGO-3.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freeze-thaw cycles.
Molecular Weight
Predicted molecular weight is ~60-80kDa depending on maturity/glycosylation.
OMIM
615689
Antigen
Fusion protein corresponding to aa 554-574, the cytoplasmic C-terminus, of human AMIGO-1 (accession no.Q86WK6).
Positive Control
Rat brain lysate.
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Applications Tested/Suitable for anti-AMIGO-1 antibody
Immunoblot (IB)
Application Notes for anti-AMIGO-1 antibody
Immunoblotting: Use at 1ug/ml.

Testing Data of anti-AMIGO-1 antibody

Mouse Anti-AMIGO-1 Monoclonal Antibody – Cat# MBS190914

Other Notes

Small volumes of anti-AMIGO-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMIGO-1 purchase

MBS190914 is an antibody targeting AMIGO-1. Also known as AMIGO-1 Monoclonal Antibody. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for AMIGO-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
amphoterin-induced protein 1
NCBI Official Synonym Full Names
adhesion molecule with Ig-like domain 1
NCBI Official Symbol
AMIGO1
NCBI Official Synonym Symbols
ALI2; AMIGO; AMIGO-1
UniProt Protein Name
Amphoterin-induced protein 1
UniProt Synonym Protein Names
AMIGO-1; Alivin-2
UniProt Gene Name
AMIGO1
UniProt Entry Name
AMGO1_HUMAN
NCBI Protein Information
amphoterin-induced protein 1

UniProt Comments for AMIGO-1

AMIGO1: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Belongs to the immunoglobulin superfamily. AMIGO family.

Protein type: Membrane protein, integral; Cell development/differentiation

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: axon; dendrite; perikaryon; voltage-gated potassium channel complex

Molecular Function: potassium channel regulator activity

Biological Process: axonal fasciculation; axonogenesis; heterophilic cell adhesion; homophilic cell adhesion; myelination; positive regulation of axonogenesis; positive regulation of synaptogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-AMIGO-1 antibody

Organs/Tissues associated with anti-AMIGO-1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with AMIGO-1 and Brain
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