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Neuroligin-1 (NLGN1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS191335

Neuroligin-1 is a neuronal cell surface protein and member of the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses, it participates in regulation of synaptic plasticity, and it is important in the… More details

$580 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Neuroligin-1 (Nlgn1), Monoclonal Antibody
Full Product Name
Neuroligin-1 Monoclonal Antibody
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Form/Format
100ug (1mg/ml) Protein G-purified antibody in PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.
Specificity
This antibody recognizes human, mouse, and rat Neuroligin-1. It does not crossreact with other Neuroligins.
Preparation and Storage
This product is stable for at least one (1) year at-20 degree C.
Molecular Weight
90,995 Da
3D Structure
ModBase 3D Structure for Q62765
Immunogen
Fusion protein corresponding to aa 718-843 (cytoplasmic C-terminus) of rat Neuroligin1, accession no. Q62765). This sequence is 99% identical to mouse and 99% identical to human Neuroligin-1.
Applications Tested/Suitable for anti-Nlgn1 antibody
Immunoblot, Immunofluorescence (IF)
Application Notes for anti-Nlgn1 antibody
Immunoblot: 1-5ug/ml. A band of ~120kDa is detected.
IF: 10ug/ml
Dilute in PBS or medium that is identical to that used in the assay system

Testing Data of anti-Nlgn1 antibody

Detection of Neuroligin-1 in mouse brain lysate at 5ug/ml.
Mouse Anti-NLGN1 Monoclonal Antibody – Cat# MBS191335

Testing Data of anti-Nlgn1 antibody

Detection of Neuroligin-1 in neuroblastoma cell line SK-N-BE at 10ug/ml: DAPI (blue) nuclear stain, Texas Red F actin stain, FITC (green) Neuroligin-1 stain.
Mouse Anti-NLGN1 Monoclonal Antibody, Testing Data – Cat# MBS191335

Other Notes

Small volumes of anti-Nlgn1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nlgn1 purchase

MBS191335 is an antibody targeting Nlgn1. Also known as Neuroligin-1 Monoclonal Antibody. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Nlgn1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuroligin-1
NCBI Official Synonym Full Names
neuroligin 1
NCBI Official Symbol
Nlgn1
UniProt Protein Name
Neuroligin-1
UniProt Synonym Protein Names
Neuroligin I
Protein Family
UniProt Gene Name
Nlgn1
NCBI Protein Information
neuroligin-1

NCBI Summary for Nlgn1

transmembrane ligand for neurexins; involved in development and maturation of synaptic connections [RGD, Feb 2006]

UniProt Comments for Nlgn1

Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-Nlgn1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >15 publications with Nlgn1 and Brain
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