Bmf (Ct) Antibody – Rabbit Polyclonal

Polyclonal

Rabbit

100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.

Bmf (CT) [This rabbit antibody recognizes an epitope of aa 171-184 at the C-terminus of human Bmf (Bcl-2-Modifying Factor), a novel BH3-only protein.]
This antibody recognizes an epitope at the C-terminus of human Bmf (Bcl-2- Modifying Factor), a novel BH3-only protein. In healthy cells, Bmf associates with the dynein light chain 2 component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiaing the downstream apoptotic program. Bmf is constitutively expressed in many tissues.

This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.

Peptide corresponding to aa 171-184 of human Bmf.

None

0.02% sodium azide

Dilute in PBS or medium which is identical to that used in the assay system.