Human GPC4 cDNA Clone Expression Plasmid – Cat# MBS1266993

GPC4 cDNA Clone – Glypican 4 (Human)

Name: GPC4 cDNA Clone; Glypican 4; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1266993
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1266993

MBS1266993 is a cDNA clone targeting GPC4. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GPC4, cDNA Clone

Full Product Name

GPC4 cDNA Clone

Product Gene Name

GPC4 cdna clone

Sequence

atggcacggt tcggcttgcc cgcgcttctc tgcaccctgg cagtgctcag cgccgcgctg ctggctgccg agctcaagtc gaaaagttgc tcggaagtgc gacgtcttta cgtgtccaaa ggcttcaaca agaacgatgc ccccctccac gagatcaacg gtgatcattt gaagatctgt ccccagggtt ctacctgctg ctctcaagag atggaggaga agtacagcct gcaaagtaaa gatgatttca aaagtgtggt cagcgaacag tgcaatcatt tgcaagctgt ctttgcttca cgttacaaga agtttgatga attcttcaaa gaactacttg aaaatgcaga gaaatccctg aatgatatgt ttgtgaagac atatggccat ttatacatgc aaaattctga gctatttaaa gatctcttcg tagagttgaa acgttactac gtggtgggaa atgtgaacct ggaagaaatg ctaaatgact tctgggctcg cctcctggag cggatgttcc gcctggtgaa ctcccagtac cactttacag atgagtatct ggaatgtgtg agcaagtata cggagcagct gaagcccttc ggagatgtcc ctcgcaaatt gaagctccag gttactcgtg cttttgtagc agcccgtact ttcgctcaag gcttagcggt tgcgggagat gtcgtgagca aggtctccgt ggtaaacccc acagcccagt gtacccatgc cctgttgaag atgatctact gctcccactg ccggggtctc gtgactgtga agccatgtta caactactgc tcaaacatca tgagaggctg tttggccaac caaggggatc tcgattttga atggaacaat ttcatagatg ctatgctgat ggtggcagag aggctagagg gtcctttcaa cattgaatcg gtcatggatc ccatcgatgt gaagatttct gatgctatta tgaacatgca ggataatagt gttcaagtgt ctcagaaggt tttccaggga tgtggacccc ccaagcccct cccagctgga cgaatttctc gttccatctc tgaaagtgcc ttcagtgctc gcttcagacc acatcacccc gaggaacgcc caaccacagc agctggcact agtttggacc gactggttac tgatgtcaag gagaaactga aacaggccaa gaaattctgg tcctcccttc cgagcaacgt ttgcaacgat gagaggatgg ctgcaggaaa cggcaatgag gatgactgtt ggaatgggaa aggcaaaagc aggtacctgt ttgcagtgac aggaaatgga ttagccaacc agggcaacaa cccagaggtc caggttgaca ccagcaaacc agacatactg atccttcgtc aaatcatggc tcttcgagtg atgaccagca agatgaagaa tgcatacaat gggaacgacg tggacttctt tgatatcagt gatgaaagta gtggagaagg aagtggaagt ggctgtgagt atcagcagtg cccttcagag tttgactaca atgccactga ccatgctggg aagagtgcca atgagaaagc cgacagtgct ggtgtccgtc ctggggcaca ggcctacctc ctcactgtct tctgcatctt gttcctggtt atgcagagag agtggagata a

Molecular Weight

54,910 Da

OMIM

300168

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GPC4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPC4. It may not necessarily be applicable to this product.

NCBI GI #

23398481

NCBI GeneID

2239

NCBI Accession #

BC017166

UniProt Secondary Accession #

Q6ZMA6; Q96L43; Q9NU08; Q9UJN1; Q9UPD9; B2R6J7; B4E2C0

UniProt Related Accession #

O75487

NCBI Official Full Name

Homo sapiens glypican 4, mRNA

NCBI Official Synonym Full Names

glypican 4

NCBI Official Symbol

GPC4

NCBI Official Synonym Symbols

K-glypican

UniProt Protein Name

Glypican-4

UniProt Synonym Protein Names

K-glypican

Protein Family

Glypican

UniProt Gene Name

GPC4

UniProt Entry Name

GPC4_HUMAN

NCBI Protein Information

glypican-4

NCBI Summary for GPC4

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]

UniProt Comments for GPC4

GPC4: Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system. Belongs to the glypican family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: Xq26.1

Cellular Component: external side of plasma membrane; Golgi lumen; integral to plasma membrane; lysosomal lumen; nucleus; plasma membrane

Biological Process: anatomical structure morphogenesis; cell proliferation; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; retinoid metabolic process

Disease: Simpson-golabi-behmel Syndrome, Type 1; Wilms Tumor 1

Research Articles on GPC4

1. Data suggest gender difference in circulating GPC4 levels in nonalcoholic fatty liver disease; GPC4 levels in women appear to correlate with cardiometabolic risk factors (adiposity/body fat distribution, insulin resistance, and arterial stiffness).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GPC4 cdna clone

Products by Pathway	Pathway Diagram
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway antibodies	A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway Diagram
Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies	Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Associated With Visual Transduction Pathway antibodies	Diseases Associated With Visual Transduction Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
HS-GAG Biosynthesis Pathway antibodies	HS-GAG Biosynthesis Pathway Diagram
HS-GAG Degradation Pathway antibodies	HS-GAG Degradation Pathway Diagram
Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway antibodies	Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway Diagram
MPS I - Hurler Syndrome Pathway antibodies	MPS I - Hurler Syndrome Pathway Diagram
MPS II - Hunter Syndrome Pathway antibodies	MPS II - Hunter Syndrome Pathway Diagram

Diseases associated with GPC4 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with GPC4 and Neoplasms
Carcinoma Antibodies	>3 publications with GPC4 and Carcinoma
Heart Defects, Congenital Antibodies	>2 publications with GPC4 and Heart Defects, Congenital
Disease Models, Animal Antibodies	>2 publications with GPC4 and Disease Models, Animal
Brain Diseases Antibodies	>1 publications with GPC4 and Brain Diseases
Ovarian Diseases Antibodies	>1 publications with GPC4 and Ovarian Diseases
Liver Diseases Antibodies	>1 publications with GPC4 and Liver Diseases
Cell Transformation, Neoplastic Antibodies	>1 publications with GPC4 and Cell Transformation, Neoplastic
Kidney Diseases Antibodies	>1 publications with GPC4 and Kidney Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with GPC4 and Carcinoma, Hepatocellular

Organs/Tissues associated with GPC4 cdna clone

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>7 publications with GPC4 and Kidney
Brain Antibodies	>7 publications with GPC4 and Brain
Embryonic Tissue Antibodies	>5 publications with GPC4 and Embryonic Tissue
Blood Antibodies	>3 publications with GPC4 and Blood
Connective Tissue Antibodies	>3 publications with GPC4 and Connective Tissue
Heart Antibodies	>3 publications with GPC4 and Heart
Ovary Antibodies	>2 publications with GPC4 and Ovary
Eye Antibodies	>2 publications with GPC4 and Eye
Lung Antibodies	>2 publications with GPC4 and Lung
Intestine Antibodies	>1 publications with GPC4 and Intestine