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PSP Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200048

Human phosphoserine phosphatase (HPSP), specific for D- and L- phosphoserine, has been identified in all human tissues. HPSP is a Mg (2+)-dependent phosphoserine phosphatase. The three dimensional structure of HPSP reveals the structural and functional role… More details

$285 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PSP, Monoclonal Antibody
Full Product Name
PSP antibody
Product Gene Name
Product Synonym Names
PSPH; Phosphoserine phosphatase Human; PSPase; PSP; EC 3.1.3.3; O-phosphoserine phosphohydrolase; L-3-phosphoserine phosphatase; Phosphoserine phosphatase; L 3 phosphoserine phosphatase; O phosphoserine phosphohydrolase; Phosphoserine phosphatase deficiency; included
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
3G12
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Purity/Purification
By protein-G affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
25,008 Da
OMIM
Y10275 mRNA
3D Structure
ModBase 3D Structure for P78330
Antigen Species
Human
Immunogen
Recombinant human PSP (1-225aa) purified from E. coli
Clone Note
Anti-human PSP mAb, clone 3G12, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PSP protein.

Product Categories/Family for anti-PSP antibody

Applications Tested/Suitable for anti-PSP antibody
ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-PSP antibody
WB: 1:1,000 ~ 2,000.
Recommended starting dilution is 1:1,000.

Western Blot (WB) of anti-PSP antibody

The recombinant mouse brain (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PSP antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : Mouse brain (1:500)
Mouse Anti-PSP Monoclonal Antibody – Cat# MBS200048

Product References and Citations for anti-PSP antibody

Moro-Furlani, et al., (1980) Ann Hum Genet 43 (4):323-3233; Kim HY, et al., (2002) J Biol Chem 277 (48):46651-46658; Peeraer Y, et al., (2004) Eur J Biochem 271 (16):3421-3427

Other Notes

Small volumes of anti-PSP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSP purchase

MBS200048 is an antibody targeting PSP. Also known as PSP antibody. Reactive in Human, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PSP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosphoserine phosphatase
NCBI Official Synonym Full Names
phosphoserine phosphatase
NCBI Official Symbol
PSPH
NCBI Official Synonym Symbols
PSP; PSPHD
UniProt Protein Name
Phosphoserine phosphatase
UniProt Synonym Protein Names
L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase
UniProt Gene Name
PSPH
UniProt Synonym Gene Names
PSP; PSPase
NCBI Protein Information
phosphoserine phosphatase

NCBI Summary for PSP

The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for PSP

Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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