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Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2001793
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MBS2001793 is an antibody targeting TNFSF14. Also known as Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14). Reactive in Mouse, Rat. Host: Rabbit. More details

$205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14)
Product Gene Name
anti-TNFSF14 antibody
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EF- TQGWFLLRLH QRLGDIVAHL PDGGKGSWEK LIQDQRSHQA NPAAHLTGAN ASLIGIGGPL LWETRLGLAF LRGLTYHDGA LVTMEPGYYY VYSKVQLSGV GCPQGLANGL PITHGLYKRT SRYPKELELL VSRRSPCGRA NSSRVWWDSS FLGGVVHLEA GEEVVVRVPG NRLVRPRDGT RSYFGAFMV
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against TNFSF14. It has been selected for its ability to recognize TNFSF14 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: TNFSF14 (MBS2001793)
Biotin Conjugated Antibody: TNFSF14 (MBS2003995)
Matching Pairs
Unconjugated Antibody: TNFSF14 (MBS2001793)
Immunogen: TNFSF14 (MBS2011378)
Show more
Molecular Weight
26,338 Da
3D Structure
ModBase 3D Structure for Q9QYH9
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant TNFSF14 (Thr51~Val239) expressed in E.coli.
Cross Reactivity
Mouse
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2048234
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-TNFSF14 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-TNFSF14 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-TNFSF14 antibody

Western Blot: Sample: Recombinant TNFSF14, Mouse.
Rabbit Anti-TNFSF14 Polyclonal Antibody – Cat# MBS2001793

Immunohistochemistry (IHC) of anti-TNFSF14 antibody

DABstainingonIHC-P.Samples:MouseTissue)
Rabbit Anti-TNFSF14 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2001793

Other Notes

Small volumes of anti-TNFSF14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TNFSF14. It may not necessarily be applicable to this product.

NCBI GI #
9507195
NCBI GeneID
50930
NCBI Accession #
NP_062291.1
UniProt Primary Accession #
Q9QYH9
UniProt Secondary Accession #
Q059Y9
UniProt Related Accession #
Q9QYH9
GenBank Nucleotide #
NM_019418.3
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 14
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 14
NCBI Official Symbol
Tnfsf14
NCBI Official Synonym Symbols
LTg; HVEML; LIGHT; Ly113; HVEM-L; Tnlg1d
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 14
UniProt Synonym Protein Names
CD_antigen: CD258
Protein Family
Tumor necrosis factor ligand superfamily
UniProt Gene Name
Tnfsf14
UniProt Synonym Gene Names
Light
NCBI Protein Information
tumor necrosis factor ligand superfamily member 14

UniProt Comments for TNFSF14

TNFSF14: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Inhibitor; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17|17 D

Cellular Component: extracellular region; extracellular space; integral component of membrane; membrane; plasma membrane

Molecular Function: caspase inhibitor activity; cytokine activity; receptor binding; tumor necrosis factor receptor binding

Biological Process: immune response; positive regulation of myoblast differentiation; release of cytoplasmic sequestered NF-kappaB; T cell costimulation
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Research Articles on TNFSF14

1. LIGHT promote myeloid differentiation of Hematopoietic stem/progenitor cells via LIGHT receptor signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TNFSF14 antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram

Diseases associated with anti-TNFSF14 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >224 publications with TNFSF14 and Necrosis
 Inflammation Antibodies  >59 publications with TNFSF14 and Inflammation
 Immune System Diseases Antibodies  >44 publications with TNFSF14 and Immune System Diseases
 Disease Models, Animal Antibodies  >21 publications with TNFSF14 and Disease Models, Animal
 Liver Diseases Antibodies  >14 publications with TNFSF14 and Liver Diseases
 Neoplasms, Experimental Antibodies  >11 publications with TNFSF14 and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >10 publications with TNFSF14 and Cardiovascular Diseases
 Lung Diseases Antibodies  >8 publications with TNFSF14 and Lung Diseases
 Brain Diseases Antibodies  >7 publications with TNFSF14 and Brain Diseases
 Breast Neoplasms Antibodies  >5 publications with TNFSF14 and Breast Neoplasms

Organs/Tissues associated with anti-TNFSF14 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >15 publications with TNFSF14 and Bone Marrow
 Skin Antibodies  >7 publications with TNFSF14 and Skin
 Thymus Antibodies  >6 publications with TNFSF14 and Thymus
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