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AKR7A3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200211

Aldo-keto reductase family 7, member A 3 (AKR7A3) is a member of the aldo/keto reductase superfamily involved in the detoxification and metabolism of a variety of exogenous aldehydes and ketones. The activity of AKR7A3 may detoxify the aflatoxin B1 (AFB1)… More details

$285 / 0.05 mL +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
AKR7A3, Monoclonal Antibody
Full Product Name
AKR7A3 antibody
Product Gene Name
Product Synonym Names
Aldo-keto reductase family 7 member A 3; Aflatoxin B1 aldehyde reductase member 3; AFB1 aldehyde reductase 2 (AFAR2); Aldo-keto reductase family 7; member A 3 AFAR 2; AFAR2; AFB1 AR 2; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase 2; Aflatoxin B1 aldehyde reductase member 3; Aldo keto reductase family 7 member A3; OTTHuMP00000002623.
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
AT2E11
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Purity/Purification
By protein-G affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
37,206 Da
OMIM
AF040639 mRNA
Antigen Species
Human
Immunogen
Recombinant human AKR7A3 (1-331aa) purified from E. coli
Clone Note
Anti-human AKR7A3 mAb, clone AT2E11, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human AKR7A3 protein.

Product Categories/Family for anti-AKR7A3 antibody

Applications Tested/Suitable for anti-AKR7A3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-AKR7A3 antibody
WB: 1:1000.

Western Blot (WB) of anti-AKR7A3 antibody

The Cell lysates (5ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human AKR7A3 antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: 293T cell lysate Lane 2.: AKR7A3 Transfected 293T cell lysate
Mouse Anti-AKR7A3 Monoclonal Antibody – Cat# MBS200211

Product References and Citations for anti-AKR7A3 antibody

Chem Res Toxicol 2008, 21:1134-1142.; J. Biol. Chem. 267 (34): 24841-7. ; Chem Res Toxicol 2008, 21:1134-1142.

Other Notes

Small volumes of anti-AKR7A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AKR7A3 purchase

MBS200211 is an antibody targeting AKR7A3. Also known as AKR7A3 antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for AKR7A3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
NCBI Official Synonym Full Names
aldo-keto reductase family 7 member A3
NCBI Official Symbol
AKR7A3
NCBI Official Synonym Symbols
AFAR2
UniProt Protein Name
Aflatoxin B1 aldehyde reductase member 3
UniProt Synonym Protein Names
AFB1 aldehyde reductase 2; AFB1-AR 2
UniProt Gene Name
AKR7A3
UniProt Synonym Gene Names
AFAR2; AFB1-AR 2
NCBI Protein Information
aflatoxin B1 aldehyde reductase member 3

NCBI Summary for AKR7A3

Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]

UniProt Comments for AKR7A3

Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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