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PAIP2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200235

PAIP2 (Poly (A)-binding protein-interacting protein 2) is a 127 amino acid protein. PAIP binds to the polyadenylate-binding protein (PABP). There are two PAIP proteins called PAIP1 and PAIP2. PAIP2 acts as a repressor in the regulation of translation… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PAIP2, Monoclonal Antibody
Full Product Name
PAIP2 antibody
Product Gene Name
Product Synonym Names
Poly (A)-binding protein-interacting protein 2; PAIP2A; PABP- interacting protein 2; HSPC218; Poly (A)-binding protein-interacting protein 2 poly (A) binding protein interacting protein 2.
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
AT1C12
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Purity/Purification
By protein-G affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
14,984 Da
OMIM
AF317675 mRNA
3D Structure
ModBase 3D Structure for Q9BPZ3
Antigen Species
Human
Immunogen
Recombinant human PAIP2 (1-127aa) purified from E. coli
Clone Note
Anti-human PAIP2 mAb, clone AT1C12, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PAIP2 protein.

Product Categories/Family for anti-PAIP2 antibody

Applications Tested/Suitable for anti-PAIP2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PAIP2 antibody
WB: 1:500 ~ 1:5000.
Recommended starting dilution is 1:1000.

Western Blot (WB) of anti-PAIP2 antibody

The extracts of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PAIP2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Mouse Anti-PAIP2 Monoclonal Antibody – Cat# MBS200235

Product References and Citations for anti-PAIP2 antibody

Khaleghpour, K., et al. (2001) Mol Cell Biol 7: 205-216; Khaleghpour, K., et al. (2001) Cell Biol 21: 5200-5213; vitkin, Y.V., et al. (2001) RNA 7: 1743-1752

Other Notes

Small volumes of anti-PAIP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAIP2 purchase

MBS200235 is an antibody targeting PAIP2. Also known as PAIP2 antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PAIP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
polyadenylate-binding protein-interacting protein 2
NCBI Official Synonym Full Names
poly(A) binding protein interacting protein 2
NCBI Official Symbol
PAIP2
NCBI Official Synonym Symbols
PAIP-2; PAIP2A
UniProt Protein Name
Polyadenylate-binding protein-interacting protein 2
UniProt Gene Name
PAIP2
UniProt Synonym Gene Names
PAIP2A; PABP-interacting protein 2; PAIP-2; Poly(A)-binding protein-interacting protein 2
NCBI Protein Information
polyadenylate-binding protein-interacting protein 2

UniProt Comments for PAIP2

Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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