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COX5A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200358

COX5A, also known as COX, COX-VA and VA, belongs to the cytochrome c oxidase subunit 5A family. Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
COX5A, Monoclonal Antibody
Full Product Name
COX5A antibody
Product Gene Name
Product Synonym Names
cytochrome c oxidase subunit Va; cytochrome c oxidase subunit Va; COX; COX-VA; VA
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
AT7A6
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Purity/Purification
By protein-A affinity chromatography
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
32,340 Da
OMIM
AJ243310 mRNA
3D Structure
ModBase 3D Structure for O95433
Antigen Species
Human
Immunogen
Recombinant human COX5A (42-150aa) purified from E. coli
Clone Note
Anti-human COX5A mAb, clone AT7A6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human COX5A protein.

Product Categories/Family for anti-COX5A antibody

Applications Tested/Suitable for anti-COX5A antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)

Western Blot (WB) of anti-COX5A antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human COX5A antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : A431 cell lysate Lane 2. : HeLa cell lysate
Mouse Anti-COX5A Monoclonal Antibody – Cat# MBS200358

Immunofluorescence (IF) of anti-COX5A antibody

ICC/IF analysis of COX5A in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human COX5A antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
Mouse Anti-COX5A Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS200358

Product References and Citations for anti-COX5A antibody

Lenka N., et al. (1998) Prog Nucleic Acid Res Mol Biol. 61: 309-344. ; Schmidt TR., et al. (2002) Gene. 286: 13-19.

Other Notes

Small volumes of anti-COX5A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COX5A purchase

MBS200358 is an antibody targeting COX5A. Also known as COX5A antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for COX5A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
activator of 90 kDa heat shock protein ATPase homolog 1 isoform 1
NCBI Official Synonym Full Names
activator of HSP90 ATPase activity 1
NCBI Official Symbol
AHSA1
NCBI Official Synonym Symbols
p38; AHA1; hAha1; C14orf3
UniProt Protein Name
Activator of 90 kDa heat shock protein ATPase homolog 1
UniProt Synonym Protein Names
p38
Protein Family
UniProt Gene Name
AHSA1
UniProt Synonym Gene Names
C14orf3; AHA1
NCBI Protein Information
activator of 90 kDa heat shock protein ATPase homolog 1

UniProt Comments for COX5A

Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-COX5A antibody

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