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V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2006540
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MBS2006540 is an antibody targeting RELB. Also known as Polyclonal Antibody to V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB). Reactive in Mouse. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB)
Product Gene Name
anti-RELB antibody
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-LVG KD CTDGVCRVRL RPHVSPRHSF NNLGIQCVRK KEIEAAIERK IQLGIDPYNA GSLKNHQEVD MNVVRICFQA SYRDQQGHLH RMDPILSEPV YDKKSTNTSE LRICRINKES GPCTGGEELY LLCDKVQKED ISVVFSTASW EGRADFSQAD VHRQIAIVFK TPPYEDLEIS EPVTVNVFLQ RLTDGVCSEP LPFTYLPRDH DSYGVDKKRK RGLPDVLGEL SSSDPHGIES KRRKKKPVFL DHFLPGHSSG LFLPPS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against RELB. It has been selected for its ability to recognize RELB in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: RELB (MBS2006540)
Immunogen: RELB (MBS2012293)
Matching Pairs
Unconjugated Antibody: RELB (MBS2006540)
APC-CY7 Conjugated Antibody: RELB (MBS2059618)
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Molecular Weight
60,305 Da
3D Structure
ModBase 3D Structure for Q04863
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant RELB (Leu176~Ser436) expressed in E.coli.
Cross Reactivity
Mouse
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2059620
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-RELB antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-RELB antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-RELB antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-RELB Polyclonal Antibody – Cat# MBS2006540

Immunohistochemistry (IHC) of anti-RELB antibody

DAB staining on IHC-P; Samples: Mouse Testis Tissue)
Rabbit Anti-RELB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2006540

Other Notes

Small volumes of anti-RELB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RELB. It may not necessarily be applicable to this product.

NCBI GI #
594190858
NCBI GeneID
19698
NCBI Accession #
NP_001277386.1
UniProt Primary Accession #
Q04863
UniProt Secondary Accession #
Q8VE46
UniProt Related Accession #
Q04863
GenBank Nucleotide #
NM_001290457.1
NCBI Official Full Name
transcription factor RelB isoform 2
NCBI Official Synonym Full Names
avian reticuloendotheliosis viral (v-rel) oncogene related B
NCBI Official Symbol
Relb
NCBI Official Synonym Symbols
shep
UniProt Protein Name
Transcription factor RelB
Protein Family
Antitoxin
UniProt Gene Name
Relb
NCBI Protein Information
transcription factor RelB

UniProt Comments for RELB

RELB: a transcription factor of the nuclear factor-kappaB (NFkB) transcription complex. Stimulates promoter activity in the presence NFkB1/NFkB-p50. Plays role in regulation of apoptosis in hepatocellular carcinoma through activation of downstream target genes. Does not associate with DNA or RelA/NFkB-p65.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 7 A3|7 9.93 cM

Cellular Component: centrosome; cytoplasm; cytoskeleton; cytosol; nucleoplasm; nucleus; protein complex

Molecular Function: chromatin binding; DNA binding; DNA binding transcription factor activity; identical protein binding; protein binding; protein kinase binding

Biological Process: antigen processing and presentation; cellular response to osmotic stress; circadian regulation of gene expression; I-kappaB kinase/NF-kappaB signaling; inflammatory response; innate immune response; lymphocyte differentiation; myeloid dendritic cell differentiation; negative regulation of interferon-beta production; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; NIK/NF-kappaB signaling; positive regulation of gene expression; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; response to cytokine; rhythmic process; T-helper 1 cell differentiation; T-helper 1 type immune response; transcription, DNA-dependent
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Research Articles on RELB

1. results suggest that changes in the relative concentrations of RelB, NIK:IKK1, and p100 during noncanonical signaling modulate this transitional complex and are critical for maintaining the fine balance between the processing and protection of p100.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RELB antibody

 Reference Product  PubMed Publications
 Tnf antibody  >169 publications with RELB and Tnf
 Nfkb2 antibody  >111 publications with RELB and Nfkb2
 Jun antibody  >99 publications with RELB and Jun
 Nfkb1 antibody  >38 publications with RELB and Nfkb1
 Chuk antibody  >35 publications with RELB and Chuk
 Bcl2l1 antibody  >15 publications with RELB and Bcl2l1
 Bcl3 antibody  >9 publications with RELB and Bcl3
 Nfkbia antibody  >7 publications with RELB and Nfkbia
 Nfkbie antibody  >6 publications with RELB and Nfkbie
 Daxx antibody  >4 publications with RELB and Daxx

Pathways associated with anti-RELB antibody

 Products by Pathway  Pathway Diagram
 Apoptosis Signaling Pathway antibodies  Apoptosis Signaling Pathway Diagram
 C-type Lectin Receptors (CLRs) Pathway antibodies  C-type Lectin Receptors (CLRs) Pathway Diagram
 CD209 (DC-SIGN) Signaling Pathway antibodies  CD209 (DC-SIGN) Signaling Pathway Diagram
 CLEC7A (Dectin-1) Signaling Pathway antibodies  CLEC7A (Dectin-1) Signaling Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Dectin-1 Mediated Noncanonical NF-kB Signaling Pathway antibodies  Dectin-1 Mediated Noncanonical NF-kB Signaling Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram

Diseases associated with anti-RELB antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >217 publications with RELB and Necrosis
 Inflammation Antibodies  >167 publications with RELB and Inflammation
 Breast Neoplasms Antibodies  >35 publications with RELB and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >21 publications with RELB and Cell Transformation, Neoplastic
 Lung Diseases Antibodies  >20 publications with RELB and Lung Diseases
 Liver Diseases Antibodies  >15 publications with RELB and Liver Diseases
 Kidney Diseases Antibodies  >14 publications with RELB and Kidney Diseases
 Chromosome Aberrations Antibodies  >11 publications with RELB and Chromosome Aberrations
 Hyperplasia Antibodies  >9 publications with RELB and Hyperplasia
 Multiple Myeloma Antibodies  >9 publications with RELB and Multiple Myeloma

Organs/Tissues associated with anti-RELB antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >101 publications with RELB and Bone
 Bone Marrow Antibodies  >79 publications with RELB and Bone Marrow
 Spleen Antibodies  >52 publications with RELB and Spleen
 Thymus Antibodies  >43 publications with RELB and Thymus
 Lung Antibodies  >43 publications with RELB and Lung
 Liver Antibodies  >35 publications with RELB and Liver
 Kidney Antibodies  >33 publications with RELB and Kidney
 Muscle Antibodies  >28 publications with RELB and Muscle
 Embryonic Tissue Antibodies  >26 publications with RELB and Embryonic Tissue
 Skin Antibodies  >25 publications with RELB and Skin
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