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Procalcitonin (PCT) Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2006803
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MBS2006803 is an antibody targeting PCT. Also known as Polyclonal Antibody to Procalcitonin (PCT). Host: Rabbit. More details

$195 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Procalcitonin (PCT), Antibody
Full Product Name
Polyclonal Antibody to Procalcitonin (PCT)
Product Gene Name
anti-PCT antibody
Host
Rabbit
Form/Format
Liquid; Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.26mg/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20°C for 24 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: PCT (MBS2006803)
Biotin Conjugated Antibody: PCT (MBS2002264)
Matching Pairs
Unconjugated Antibody: PCT (MBS2006803)
Immunogen: PCT (MBS2018533)
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OMIM
X00356 mRNA
3D Structure
ModBase 3D Structure for P01258
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Cross Reactivity
Mouse
Immunogen
Recombinant PCT (Ala26~Asn141) expressed in E.coli
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PCT antibody
Western Blot (WB)
Application Notes for anti-PCT antibody
Western blotting: 0.01-2ug/mL

Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-PCT antibody

Figure. Western Blot; Sample: Recombinant PCT, Human.
Rabbit Anti-PCT Antibody – Cat# MBS2006803

Western Blot (WB) of anti-PCT antibody

Western Blot; Sample: Mouse Pancreas lysate;
Primary Ab: 2ug/ml Rabbit Anti-Human PCT Antibody
Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: MBS2086047)
Rabbit Anti-PCT Antibody, Western Blot (WB) – Cat# MBS2006803

Immunohistochemistry (IHC) of anti-PCT antibody

DAB staining on IHC-P; Samples: Human Kidney Tissue;
Primary Ab: 20ug/ml Rabbit Anti-Human PCT Antibody
Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: MBS2086047)
Rabbit Anti-PCT Antibody, Immunohistochemistry (IHC) – Cat# MBS2006803

Immunohistochemistry (IHC) of anti-PCT antibody

DAB staining on IHC-P
Samples: Human Cerebrum Tissue
Primary Ab: 20ug/ml Rabbit Anti-Human PCT Antibody
Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 )
Rabbit Anti-PCT Antibody, Immunohistochemistry (IHC) – Cat# MBS2006803

Other Notes

Small volumes of anti-PCT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PCT. It may not necessarily be applicable to this product.

NCBI GI #
76880484
NCBI GeneID
796
NCBI Accession #
NP_001029124.1
UniProt Primary Accession #
P01258
UniProt Secondary Accession #
Q13935; Q13937; Q52LX7; B7ZL39
UniProt Related Accession #
P01258; P06881
GenBank Nucleotide #
NM_001033952.2
NCBI Official Full Name
calcitonin isoform CT preproprotein
NCBI Official Synonym Full Names
calcitonin related polypeptide alpha
NCBI Official Symbol
CALCA
NCBI Official Synonym Symbols
CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I
UniProt Protein Name
Calcitonin
UniProt Synonym Protein Names
CalcitoninKatacalcinAlternative name(s):Calcitonin carboxyl-terminal peptide; CCP
UniProt Gene Name
CALCA
UniProt Synonym Gene Names
CALC1; CCP
NCBI Protein Information
calcitonin; calcitonin gene-related peptide 1

NCBI Summary for PCT

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
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UniProt Comments for PCT

CALCA: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.2

Cellular Component: cell soma; cytoplasm; extracellular region; extracellular space; nucleus; terminal bouton

Molecular Function: calcitonin receptor binding; hormone activity; identical protein binding; protein binding

Biological Process: activation of protein kinase activity; adenylate cyclase activation; adenylate cyclase-activating G-protein coupled receptor signaling pathway; aging; cellular protein metabolic process; detection of temperature stimulus involved in sensory perception of pain; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); embryo implantation; feeding behavior; inflammatory response; monocyte chemotaxis; negative regulation of bone resorption; negative regulation of neurological process; negative regulation of ossification; negative regulation of smooth muscle contraction; negative regulation of transcription, DNA-dependent; neuropeptide signaling pathway; positive regulation of adenylate cyclase activity; positive regulation of ossification; regulation of heart rate; response to heat; response to pain; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure
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Research Articles on PCT

1. Serum procalcitonin levels are elevated in bacteremia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PCT antibody

 Reference Product  PubMed Publications
 RAMP1 antibody  >2 publications with PCT and RAMP1
 IAPP antibody  >1 publications with PCT and IAPP
 ADM antibody  >1 publications with PCT and ADM
 CALCRL antibody  >1 publications with PCT and CALCRL

Pathways associated with anti-PCT antibody

 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Calcitonin-like Ligand Receptors Pathway antibodies  Calcitonin-like Ligand Receptors Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Endothelin Pathway antibodies  Endothelin Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-PCT antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with PCT and Inflammation
 Pain Antibodies  >3 publications with PCT and Pain
 Hypertension Antibodies  >3 publications with PCT and Hypertension
 Kidney Diseases Antibodies  >3 publications with PCT and Kidney Diseases
 Neurogenic Inflammation Antibodies  >2 publications with PCT and Neurogenic Inflammation
 Migraine Disorders Antibodies  >2 publications with PCT and Migraine Disorders
 Drug Toxicity Antibodies  >2 publications with PCT and Drug Toxicity
 Headache Antibodies  >2 publications with PCT and Headache
 Edema Antibodies  >2 publications with PCT and Edema
 Necrosis Antibodies  >1 publications with PCT and Necrosis

Organs/Tissues associated with anti-PCT antibody

 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >9 publications with PCT and Thyroid
 Brain Antibodies  >6 publications with PCT and Brain
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