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Complexin 2 (CPLX2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2007121
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2007121 is an antibody targeting CPLX2. Also known as Polyclonal Antibody to Complexin 2 (CPLX2). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Complexin 2 (CPLX2), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Complexin 2 (CPLX2)
Product Gene Name
Immunogen Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF-DFVMKQ ALG GATKDMGKML GGEEEKDPDA QKKEEERQEA LRQQEEERKA KHARMEAERE KVRQQIRDKY GLKKKEEKEA EEKAALEQPC EGSLTRPKKA IPAGCGDEEE EEEESILDTV LKYLPGPLQD MFKK
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against CPLX2. It has been selected for its ability to recognize CPLX2 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: CPLX2 (MBS2007121)
Immunogen: CPLX2 (MBS2011040)
Matching Pairs
Unconjugated Antibody: CPLX2 (MBS2007121)
APC-CY7 Conjugated Antibody: CPLX2 (MBS2076277)
Molecular Weight
15,394 Da
OMIM
U35100 mRNA
3D Structure
ModBase 3D Structure for Q6PUV4
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant CPLX2 (Asp2~Lys134) expressed in E.coli.
Cross Reactivity
Human, Mouse, Rat
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2076279
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CPLX2 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-CPLX2 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-CPLX2 antibody

Western Blot: Sample: Rat Spinal cord lysate; Primary Ab: 1ug/ml Rabbit Anti-Human CPLX2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Rabbit Anti-CPLX2 Polyclonal Antibody – Cat# MBS2007121

Western Blot (WB) of anti-CPLX2 antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-CPLX2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2007121

Immunohistochemistry (IHC) of anti-CPLX2 antibody

DAB staining on IHC-P. Samples: Human Tissue)
Rabbit Anti-CPLX2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2007121

Other Notes

Small volumes of anti-CPLX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CPLX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
complexin-2
NCBI Official Synonym Full Names
complexin 2
NCBI Official Symbol
CPLX2
NCBI Official Synonym Symbols
CPX2; Hfb1; 921-L; CPX-2
UniProt Protein Name
Complexin-2
UniProt Synonym Protein Names
Complexin II; CPX II; Synaphin-1
Protein Family
UniProt Gene Name
CPLX2
UniProt Synonym Gene Names
CPX II
NCBI Protein Information
complexin-2

NCBI Summary for CPLX2

Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for CPLX2

CPLX2: Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis. Belongs to the complexin/synaphin family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 5q35.2

Cellular Component: cell soma; cytosol; dendrite; mast cell granule; terminal bouton

Molecular Function: calcium-dependent protein binding; syntaxin-1 binding

Biological Process: cell differentiation; mast cell degranulation; nervous system development; positive regulation of synaptic plasticity; regulation of exocytosis; synaptic vesicle exocytosis; vesicle docking involved in exocytosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CPLX2 antibody

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