Alcohol Dehydrogenase 1 (ADH1) Antibody – Rabbit Polyclonal

ADH1C: class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Mitochondrial; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450

Chromosomal Location of Human Ortholog: 3 G3|3 64.16 cM

Cellular Component: cytoplasm; cytosol; intracellular; mitochondrion; nucleoplasm; plasma membrane

Molecular Function: alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; drug binding; ethanol binding; metal ion binding; NAD binding; oxidoreductase activity; protein homodimerization activity; retinol dehydrogenase activity; zinc ion binding

Biological Process: acetaldehyde biosynthetic process; behavioral response to ethanol; ethanol catabolic process; ethanol oxidation; response to retinoic acid; response to steroid hormone; response to testosterone stimulus; retinoic acid metabolic process; retinoid metabolic process; retinol metabolic process