CALU Recombinant Protein – Cat# MBS203316

Calumenin (CALU) Recombinant Protein

Name: CALU Recombinant Protein; Calumenin; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203316
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203316

Calumenin, also known as CALu, is a multiple EF-hand calcium-binding protein located in endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) of mammalian tissues. This protein binds 7 calcium ions with a low affinity and is involved in such ER functions… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Calumenin, Recombinant Protein

Full Product Name

Calumenin, 20-315aa, Human, His tag, E Coli

Product Gene Name

CALU recombinant protein

Product Synonym Names

Calumenin; CALu; Crocalbin; FLJ90608; IEF SSP 9302

Sequence

MGSSHHHHHH SSGLVPRGSH MKPTEKKDRV HHEPQLSDKV HNDAQSFDYD HDAFLGAEEA KTFDQLTPEE SKERLGKIVS KIDGDKDGFV TVDELKDWIK FAQKRWIYED VERQWKGHDL NEDGLVSWEE YKNATYGYVL DDPDPDDGFN YKQMMVRDER RFKMADKDGD LIATKEEFTA FLHPEEYDYM KDIVVQETME DIDKNADGFI DLEEYIGDMY SHDGNTDEPE WVKTEREQFV EFRDKNRDGK MDKEETKDWI LPSDYDHAEA EARHLVYESD QNKDGKLTKE EIVDKYDLFV GSQATDFGEA LVRHDEF

Host

E Coli

Form/Format

Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol.

Purity/Purification

> 90% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

37.2 kDa (317aa), confirmed by MALDI-TOF.

OMIM

U67280 mRNA

3D Structure

ModBase 3D Structure for O43852

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for CALU recombinant protein

Heat Shock Proteins

Applications Tested/Suitable for CALU recombinant protein

SDS-PAGE

Product References and Citations for CALU recombinant protein

Yabe D., et al. (1997) J Biol Chem. 272 (29):18232-9.; Vorum H., et al. (1998) Biochim Biophys Acta. 1386 (1):121-31.;

Other Notes

Small volumes of CALU recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CALU purchase

MBS203316 is a recombinant protein targeting CALU. Also known as Calumenin, 20-315aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CALU. It may not necessarily be applicable to this product.

NCBI GI #

4502551

NCBI GeneID

813

NCBI Accession #

NP_001210

UniProt Primary Accession #

O43852

UniProt Secondary Accession #

B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57

UniProt Related Accession #

O43852

GenBank Nucleotide #

NM_001219.4

NCBI Official Full Name

calumenin isoform a

NCBI Official Synonym Full Names

calumenin

NCBI Official Symbol

CALU

UniProt Protein Name

Calumenin

UniProt Synonym Protein Names

Crocalbin; IEF SSP 9302

Protein Family

Calumenin

UniProt Gene Name

CALU

NCBI Protein Information

calumenin

NCBI Summary for CALU

The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

UniProt Comments for CALU

Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity ().

Research Articles on CALU

1. The Calumenin modulates Sarco/Endoplasmic reticulumCa2+ATPase (SERCA) pump activity without drastically affecting ER-Ca(2+) concentration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CALU recombinant protein

Reference Product	PubMed Publications
VCP recombinant protein	>1 publications with CALU and VCP

Pathways associated with CALU recombinant protein

Products by Pathway	Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
NOTCH1 Regulation Of Human Endothelial Cell Calcification Pathway antibodies	NOTCH1 Regulation Of Human Endothelial Cell Calcification Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Platelet Degranulation Pathway antibodies	Platelet Degranulation Pathway Diagram
Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies	Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram

Diseases associated with CALU recombinant protein

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>406 publications with CALU and Lung Diseases
Lung Neoplasms Antibodies	>342 publications with CALU and Lung Neoplasms
Fibrosis Antibodies	>205 publications with CALU and Fibrosis
Inflammation Antibodies	>74 publications with CALU and Inflammation
Neoplasms, Experimental Antibodies	>57 publications with CALU and Neoplasms, Experimental
Necrosis Antibodies	>37 publications with CALU and Necrosis
Neoplasm Invasiveness Antibodies	>20 publications with CALU and Neoplasm Invasiveness
Liver Neoplasms Antibodies	>11 publications with CALU and Liver Neoplasms
Liver Diseases Antibodies	>11 publications with CALU and Liver Diseases
Brain Diseases Antibodies	>10 publications with CALU and Brain Diseases

Organs/Tissues associated with CALU recombinant protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>778 publications with CALU and Lung
Blood Antibodies	>124 publications with CALU and Blood
Vascular Antibodies	>57 publications with CALU and Vascular
Kidney Antibodies	>43 publications with CALU and Kidney
Trachea Antibodies	>38 publications with CALU and Trachea
Brain Antibodies	>36 publications with CALU and Brain
Liver Antibodies	>32 publications with CALU and Liver
Muscle Antibodies	>29 publications with CALU and Muscle
Intestine Antibodies	>22 publications with CALU and Intestine
Prostate Antibodies	>19 publications with CALU and Prostate