Serum Amyloid A (SAA1) Recombinant Protein

Serum amyloid A1 (SAA1) protein is made primarily in the liver and circulates in low levels in the blood. This protein appears to play a role in the immune system. Levels of this protein increase in the blood and other tissues under conditions of inflammation. SAA1 may help repair damaged tissues, acts as an antibacterial agent, and signal the migration of germ-fighting cells to sites of infection. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid arthritis. Recombinant Serum amyloid A protein was expressed in E Coli and purified by using conventional chromatography techniques.

Betts JC., et al. (1991) Scand J Immunol. 34 (4):471-82. ; Yilmaz E., et al. (2003) Turk J Pediatr. 45 (3):198-202.;

Small volumes of SAA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS203374 is a recombinant protein targeting SAA1. Also known as Serum amyloid A, 19-122aa, Human, His tag, E Coli. Host: E Coli.