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HRSP12 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203970

HRSP12, also called ribonuclease uK114, is an endoribonuclease found predominantly in human adult kidney and liver, and which is responsible for inhibiting translation by cleaving mRNA. This protein cleaves phosphodiester bonds only in single-stranded RNA. It… More details

$230 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HRSP12, Recombinant Protein
Full Product Name
HRSP12, 1-137aa, Human, His tag, E Coli
Product Synonym Names
Ribonuclease uK114; p14.5; PSP; uK114
Sequence
MGSSHHHHHH SSGLVPRGSH MSSLIRRVIS TAKAPGAIGP YSQAVLVDRT IYISGQIGMD PSSGQLVSGG VAEEAKQALK NMGEILKAAG CDFTNVVKTT VLLADINDFN TVNEIYKQYF KSNFPARAAY QVAALPKGSR IEIEAVAIQG PLTTASL
Host
E Coli
Form/Format
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl, 1mM DTT
Purity/Purification
> 95% by SDS-PAGE
Concentration
1.0 mg/ml (determined by BCA assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
16.6 kDa (157aa), confirmed by MALDI-TOF
OMIM
X95384 mRNA
3D Structure
ModBase 3D Structure for P52758
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for HRSP12 recombinant protein

Applications Tested/Suitable for HRSP12 recombinant protein
SDS-PAGE

Product References and Citations for HRSP12 recombinant protein

Schmiedeknecht G., et al. (1996). Eur J Biochem. 242 (2):339-51.; Manjasetty BA, et al. (2004). Proteins 54 (4):797-800

Other Notes

Small volumes of HRSP12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HRSP12 purchase

MBS203970 is a recombinant protein targeting HRSP12. Also known as HRSP12, 1-137aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for HRSP12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
2-iminobutanoate/2-iminopropanoate deaminase
NCBI Official Synonym Full Names
reactive intermediate imine deaminase A homolog
NCBI Official Symbol
RIDA
NCBI Official Synonym Symbols
PSP; P14.5; UK114; HRSP12; hp14.5
UniProt Protein Name
2-iminobutanoate/2-iminopropanoate deaminase
UniProt Synonym Protein Names
14.5 kDa translational inhibitor protein
Protein Family
UniProt Gene Name
RIDA
UniProt Synonym Gene Names
p14.5
NCBI Protein Information
2-iminobutanoate/2-iminopropanoate deaminase

UniProt Comments for HRSP12

Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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