• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ARL2 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203986

ARL2 belongs to the ADP-ribosylation factor (ARF) family. This protein functions as a component of a secretory pathway that is involved in the Ca2-dependent release of acetylcholine. It plays a role in the folding of tubule proteins, thereby playing an… More details

$230 / 0.02 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARL2, Recombinant Protein
Full Product Name
ARL2, 1-184aa, Human, His tag, E Coli
Product Gene Name
ARL2 recombinant protein
Product Synonym Names
ADP-ribosylation factor-like protein 2; ARFL2
Sequence
MGSSHHHHHH SSGLVPRGSH MGLLTILKKM KQKERELRLL MLGLDNAGKT TILKKFNGED IDTISPTLGF NIKTLEHRGF KLNIWDVGGQ KSLRSYWRNY FESTDGLIWV VDSADRQRMQ DCQRELQSLL VEERLAGATL LIFANKQDLP GALSSNAIRE ALELDSIRSH HWCIQGCSAV TGENLLPGID WLLDDISSRI FTAD
Host
E Coli
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 0.1 mM PMSF, 1mM DTT, 40% glycerol
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
23.0 kDa (204aa), confirmed by MALDI-TOF
OMIM
L13687 mRNA
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for ARL2 recombinant protein

Signal Transduction
Applications Tested/Suitable for ARL2 recombinant protein
SDS-PAGE

SDS-Page of ARL2 recombinant protein

ARL2 Recombinant Protein – Cat# MBS203986

Product References and Citations for ARL2 recombinant protein

Smith DF., et al. (2010) Mol Biochem Parasitol. 173 (2):123-31.; Dumontet C., et al (2009) PLoS One. 4 (10):e7478.

Other Notes

Small volumes of ARL2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARL2 purchase

MBS203986 is a recombinant protein targeting ARL2. Also known as ARL2, 1-184aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ARL2. It may not necessarily be applicable to this product.

NCBI GI #
20147669
NCBI GeneID
402
NCBI Accession #
AAM12602
UniProt Secondary Accession #
Q9BUK8; G3V184
UniProt Related Accession #
P36404
NCBI Official Full Name
ADP-ribosylation factor-like protein 2
NCBI Official Synonym Full Names
ADP ribosylation factor like GTPase 2
NCBI Official Symbol
ARL2
NCBI Official Synonym Symbols
ARFL2
UniProt Protein Name
ADP-ribosylation factor-like protein 2
Protein Family
ADP-ribosylation factor-like protein
UniProt Gene Name
ARL2
NCBI Protein Information
ADP-ribosylation factor-like protein 2

NCBI Summary for ARL2

This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes. [provided by RefSeq, Jul 2008]

UniProt Comments for ARL2

Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca2+-dependent release of acetylcholine. Required for normal progress through the cell cycle.
Show more

Research Articles on ARL2

1. conclude that the TBCD*ARL2*beta-tubulin complex represents a functional intermediate in the beta-tubulin folding pathway whose activity is regulated by the cycling of nucleotides on ARL2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ARL2 recombinant protein

 Reference Product  PubMed Publications
 UNC119 recombinant protein  >11 publications with ARL2 and UNC119
 ARL2BP recombinant protein  >11 publications with ARL2 and ARL2BP
 TBCD recombinant protein  >9 publications with ARL2 and TBCD

Pathways associated with ARL2 recombinant protein

 Products by Pathway  Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-chaperonin Tubulin Folding Pathway antibodies  Post-chaperonin Tubulin Folding Pathway Diagram
 Protein Folding Pathway antibodies  Protein Folding Pathway Diagram
 Regulation Of Insulin Secretion Pathway antibodies  Regulation Of Insulin Secretion Pathway Diagram

Diseases associated with ARL2 recombinant protein

 Disease Name  Pubmed Publications
 Death Antibodies  >3 publications with ARL2 and Death
 Liver Neoplasms Antibodies  >2 publications with ARL2 and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with ARL2 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with ARL2 and Carcinoma, Hepatocellular
 Wasting Syndrome Antibodies  >1 publications with ARL2 and Wasting Syndrome
 Uterine Cervical Neoplasms Antibodies  >1 publications with ARL2 and Uterine Cervical Neoplasms
 Atrophy Antibodies  >1 publications with ARL2 and Atrophy
 Disease Models, Animal Antibodies  >1 publications with ARL2 and Disease Models, Animal
 Kidney Diseases Antibodies  >1 publications with ARL2 and Kidney Diseases
 Necrosis Antibodies  >1 publications with ARL2 and Necrosis

Organs/Tissues associated with ARL2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >15 publications with ARL2 and Eye
 Brain Antibodies  >11 publications with ARL2 and Brain
 Kidney Antibodies  >5 publications with ARL2 and Kidney
 Muscle Antibodies  >4 publications with ARL2 and Muscle
 Liver Antibodies  >3 publications with ARL2 and Liver
 Heart Antibodies  >2 publications with ARL2 and Heart
 Lung Antibodies  >2 publications with ARL2 and Lung
 Prostate Antibodies  >1 publications with ARL2 and Prostate
 Bone Antibodies  >1 publications with ARL2 and Bone
 Pancreas Antibodies  >1 publications with ARL2 and Pancreas
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000