CRYGC Recombinant Protein

Name: CRYGC Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204341
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204341

Gamma-crystallin C, also known as CRYGC, belongs to the beta/gamma-crystallin family. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Gamma-crystallins are a… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CRYGC, Recombinant Protein

Full Product Name

CRYGC, 1-174aa, Human, His tag, E Coli

Product Gene Name

CRYGC recombinant protein

Product Synonym Names

Gamma-crystallin C; CCL; CRYG3

Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMGKITF YEDRAFQGRS YETTTDCPNL QPYFSRCNSI RVESGCWMLY ERPNYQGQQY LLRRGEYPDY QQWMGLSDSI RSCCLIPQTV SHRLRLYERE DHKGLMMELS EDCPSIQDRF HLSEIRSLHV LEGCWVLYEL PNYRGRQYLL RPQEYRRCQD WGAMDAKAGS LRRVVDLY

Host

E Coli

Form/Format

Liquid. In 20 mM Tris-HCl Buffer, pH8.0, 10% glycerol, 2mM DTT, 200mM NaCl

Purity/Purification

> 95% by SDS-PAGE

Concentration

1mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

23.5kDa (198aa), confirmed by MALDI-TOF

3D Structure

ModBase 3D Structure for P07315

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for CRYGC recombinant protein

Neuroscience

Applications Tested/Suitable for CRYGC recombinant protein

SDS-PAGE

Product References and Citations for CRYGC recombinant protein

Slingsby C, et al. (2000) Eye (London, England) 13 (Pt 3b): 395-402. ; Ren Z., et al. (2000) Hum. Genet. 106:531-537

Other Notes

Small volumes of CRYGC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRYGC purchase

MBS204341 is a recombinant protein targeting CRYGC. Also known as CRYGC, 1-174aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CRYGC. It may not necessarily be applicable to this product.

NCBI GI #

10518338

NCBI GeneID

1420

NCBI Accession #

NP_066269

UniProt Primary Accession #

P07315

UniProt Secondary Accession #

Q53R50

UniProt Related Accession #

P07315

GenBank Nucleotide #

NM_020989.3

NCBI Official Full Name

gamma-crystallin C

NCBI Official Synonym Full Names

crystallin gamma C

NCBI Official Symbol

CRYGC

NCBI Official Synonym Symbols

CCL; CRYG3; CTRCT2

UniProt Protein Name

Gamma-crystallin C

UniProt Synonym Protein Names

Gamma-C-crystallin; Gamma-crystallin 2-1; Gamma-crystallin 3

Protein Family

Gamma-crystallin

UniProt Gene Name

CRYGC

UniProt Synonym Gene Names

CRYG3

NCBI Protein Information

gamma-crystallin C

NCBI Summary for CRYGC

This gene encodes a member of the beta/gamma-crystallin family of proteins. Crystallins constitute the major proteins of vertebrate eye lens and maintain the transparency and refractive index of the lens. This gene and several family members are present in a gene cluster on chromosome 2. Mutations in this gene have been shown to cause multiple types of cataract, including Coppock-like cataract and zonular pulverulent cataract, among others. [provided by RefSeq, Jan 2015]

UniProt Comments for CRYGC

Crystallins are the dominant structural components of the vertebrate eye lens.

Research Articles on CRYGC

1. the G129C mutation in gammaC-crystallin, which is associated with autosomal dominant congenital nuclear cataract, perturbed the unfolding process by promoting the accumulation of two distinct aggregation-prone intermediates under mild denaturing conditions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CRYGC recombinant protein

Reference Product	PubMed Publications
CRYAA recombinant protein	>28 publications with CRYGC and CRYAA
GJA8 recombinant protein	>18 publications with CRYGC and GJA8
CRYAB recombinant protein	>15 publications with CRYGC and CRYAB
GJA3 recombinant protein	>14 publications with CRYGC and GJA3
CRYGB recombinant protein	>10 publications with CRYGC and CRYGB
BFSP2 recombinant protein	>5 publications with CRYGC and BFSP2

Diseases associated with CRYGC recombinant protein

Disease Name	Pubmed Publications
Cataract Antibodies	>52 publications with CRYGC and Cataract
Nerve Degeneration Antibodies	>1 publications with CRYGC and Nerve Degeneration

Organs/Tissues associated with CRYGC recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>35 publications with CRYGC and Eye