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PTPMT1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204505

PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DuSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic beta cells. This… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PTPMT1, Recombinant Protein
Full Product Name
PTPMT1, 28-201aa, Human, His tag E Coli
Product Synonym Names
Protein tyrosine phosphatase mitochondrial 1; Protein tyrosine phosphatase; mitochondrial 1; DuSP23; FLJ46081; MOSP; PLIP; PNAS-129
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMKVPGR AHRDWYHRID PTVLLGALPL RSLTRQLVQD ENVRGVITMN EEYETRFLCN SSQEWKRLGV EQLRLSTVDM TGIPTLDNLQ KGVQFALKYQ SLGQCVYVHC KAGRSRSATM VAAYLIQVHK WSPEEAVRAI AKIRSYIHIR PGQLDVLKEF HKQITARATK DGTFVISKT
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.
Purity/Purification
> 95% by SDS-PAGE
Concentration
1 mg/ml (determined by Bradford) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
22.6 kDa (199aa), confirmed by MALDI-TOF
OMIM
AY333987 mRNA
3D Structure
ModBase 3D Structure for Q8WUK0
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for PTPMT1 recombinant protein

Applications Tested/Suitable for PTPMT1 recombinant protein
SDS-PAGE

Product References and Citations for PTPMT1 recombinant protein

Pagliarini DJ., et al. (2005) Mol Cell. 19 (2):197-207.; Merlot S., et al. (2003) J Biol Chem. 278 (41):39866-73.

Other Notes

Small volumes of PTPMT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTPMT1 purchase

MBS204505 is a recombinant protein targeting PTPMT1. Also known as PTPMT1, 28-201aa, Human, His tag E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPMT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 isoform 1
NCBI Official Synonym Full Names
protein tyrosine phosphatase, mitochondrial 1
NCBI Official Symbol
PTPMT1
NCBI Official Synonym Symbols
MOSP; PLIP; DUSP23; PNAS-129
UniProt Protein Name
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
UniProt Synonym Protein Names
PTEN-like phosphatase; Phosphoinositide lipid phosphatase; Protein-tyrosine phosphatase mitochondrial 1 (EC:3.1.3.16, EC:3.1.3.48)
UniProt Gene Name
PTPMT1
UniProt Synonym Gene Names
MOSP; PLIP
NCBI Protein Information
phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

UniProt Comments for PTPMT1

Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTPMT1 recombinant protein

 Reference Product  PubMed Publications
 PGS1 recombinant protein  >1 publications with PTPMT1 and PGS1
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