METAP1D Recombinant Protein

Name: METAP1D Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204921
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204921

Methionine aminopeptidase 1D, mitochondrial precursor, also known as METAP1D, is a 335 amino acid mitochondrial protein that belongs to the peptidase M24A family. It is overexpressed in colon cancer cell lines, suggesting a role in tumorigenesis. METAP1D has… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

METAP1D, Recombinant Protein

Full Product Name

METAP1D, 20-335aa, Human, His tag, E Coli

Product Gene Name

METAP1D recombinant protein

Product Synonym Names

Methionine aminopeptidase 1D mitochondrial precursor; Methionine aminopeptidase 1D; mitochondrial precursor; MAP1D; Metap1l

Sequence

MGSSHHHHHH SSGLVPRGSH MGSSSPLNHI YLHKQSSSQQ RRNFFFRRQR DISHSIVLPA AVSSAHPVPK HIKKPDYVTT GIVPDWGDSI EVKNEDQIQG LHQACQLARH VLLLAGKSLK VDMTTEEIDA LVHREIISHN AYPSPLGYGG FPKSVCTSVN NVLCHGIPDS RPLQDGDIIN IDVTVYYNGY HGDTSETFLV GNVDECGKKL VEVARRCRDE AIAACRAGAP FSVIGNTISH ITHQNGFQVC PHFVGHGIGS YFHGHPEIWH HANDSDLPME EGMAFTIEPI ITEGSPEFKV LEDAWTVVSL DNQRSAQFEH TVLITSRGAQ ILTKLPHEA

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT

Purity/Purification

> 85% by SDS-PAGE

Concentration

0.25mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

37.4 kDa (339aa) confirmed by MALDI-TOF

OMIM

AY374142 mRNA

3D Structure

ModBase 3D Structure for Q6UB28

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for METAP1D recombinant protein

Immunology

Applications Tested/Suitable for METAP1D recombinant protein

SDS-PAGE

Product References and Citations for METAP1D recombinant protein

Leszczyniecka M., et al. (2006) Oncogene. 25: 3471-3478.; Serero A., et al. (2003) J Biol Chem. 278: 52953-52963.;

Other Notes

Small volumes of METAP1D recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for METAP1D purchase

MBS204921 is a recombinant protein targeting METAP1D. Also known as METAP1D, 20-335aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for METAP1D. It may not necessarily be applicable to this product.

NCBI GI #

40385867

NCBI GeneID

254042

NCBI Accession #

NP_954697

UniProt Primary Accession #

Q6UB28

UniProt Secondary Accession #

Q1WNX3

UniProt Related Accession #

Q6UB28

GenBank Nucleotide #

NM_199227.2

NCBI Official Full Name

methionine aminopeptidase 1D, mitochondrial isoform 1

NCBI Official Synonym Full Names

methionyl aminopeptidase type 1D, mitochondrial

NCBI Official Symbol

METAP1D

NCBI Official Synonym Symbols

MAP1D; MAP 1D; Metap1l; MetAP 1D

UniProt Protein Name

Methionine aminopeptidase 1D, mitochondrial

UniProt Synonym Protein Names

Methionyl aminopeptidase type 1D, mitochondrial; Peptidase M 1D

UniProt Gene Name

METAP1D

UniProt Synonym Gene Names

MAP1D; MAP 1D; MetAP 1D

NCBI Protein Information

methionine aminopeptidase 1D, mitochondrial

NCBI Summary for METAP1D

The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]).[supplied by OMIM, Mar 2008]

UniProt Comments for METAP1D

Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (). May play a role in colon tumorigenesis.

Research Articles on METAP1D

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with METAP1D recombinant protein

Organ/Tissue Name	Pubmed Publications
Mammary Gland Antibodies	>1 publications with METAP1D and Mammary Gland
Brain Antibodies	>1 publications with METAP1D and Brain