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PLXND1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7052885

Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLXND1, Polyclonal Antibody
Full Product Name
PLXND1 Antibody
Product Gene Name
anti-PLXND1 antibody
Product Synonym Names
Plexin-D1; PLXND1; KIAA0620
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: PLXND1 (MBS7052885)
HRP Conjugated Antibody: PLXND1 (MBS7052886)
Matching Pairs
Unconjugated Antibody: PLXND1 (MBS7052885)
FITC Conjugated Antibody: PLXND1 (MBS7052887)
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Molecular Weight
195,558 Da
OMIM
AB014520 mRNA
3D Structure
ModBase 3D Structure for Q9Y4D7
Immunogen
Recombinant Human Plexin-D1 protein (1-222AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PLXND1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-PLXND1 antibody
IHC: 1:20-1:200
IF: 1:50-1:200

Immunohistochemistry (IHC) of anti-PLXND1 antibody

Immunohistochemistry of paraffin-embedded human liver tissue using MBS7052885 at dilution of 1:100
Rabbit Anti-PLXND1 Polyclonal Antibody – Cat# MBS7052885

Immunohistochemistry (IHC) of anti-PLXND1 antibody

Immunohistochemistry of paraffin-embedded human brain tissue using MBS7052885 at dilution of 1:100
Rabbit Anti-PLXND1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7052885

Immunohistochemistry (IHC) of anti-PLXND1 antibody

Immunofluorescent analysis of A549 cells using MBS7052885 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-PLXND1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7052885

Other Notes

Small volumes of anti-PLXND1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLXND1 purchase

MBS7052885 is an antibody targeting PLXND1. Also known as PLXND1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLXND1. It may not necessarily be applicable to this product.

NCBI GI #
157694524
NCBI GeneID
23129
NCBI Accession #
NP_055918.2
UniProt Primary Accession #
Q9Y4D7
UniProt Secondary Accession #
Q6PJS9; Q8IZJ2; Q9BTQ2; A7E2C6; C9JPZ6
UniProt Related Accession #
Q9Y4D7
GenBank Nucleotide #
NM_015103.2
NCBI Official Full Name
plexin-D1
NCBI Official Synonym Full Names
plexin D1
NCBI Official Symbol
PLXND1
NCBI Official Synonym Symbols
PLEXD1
UniProt Protein Name
Plexin-D1
Protein Family
Plexin
UniProt Gene Name
PLXND1
UniProt Synonym Gene Names
KIAA0620
NCBI Protein Information
plexin-D1

UniProt Comments for PLXND1

PLXND1: Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. Belongs to the plexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: integral to plasma membrane; lamellipodium; plasma membrane

Molecular Function: protein binding; protein domain specific binding; semaphorin receptor activity

Biological Process: angiogenesis; branchiomotor neuron axon guidance; endothelial cell migration; regulation of angiogenesis; regulation of axon extension involved in axon guidance; regulation of cell migration; synaptogenesis
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Research Articles on PLXND1

1. Plexin D1 plays a role in collagen contraction in human lung fibroblasts.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLXND1 antibody

 Reference Product  PubMed Publications
 SEMA3E antibody  >30 publications with PLXND1 and SEMA3E
 RRAS antibody  >3 publications with PLXND1 and RRAS
 SEMA3C antibody  >3 publications with PLXND1 and SEMA3C
 NRP1 antibody  >2 publications with PLXND1 and NRP1
 SEMA4A antibody  >2 publications with PLXND1 and SEMA4A
 RND2 antibody  >2 publications with PLXND1 and RND2

Pathways associated with anti-PLXND1 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Other Semaphorin Interactions Pathway antibodies  Other Semaphorin Interactions Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram

Diseases associated with anti-PLXND1 antibody

 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >5 publications with PLXND1 and Heart Diseases
 Nervous System Diseases Antibodies  >4 publications with PLXND1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >3 publications with PLXND1 and Disease Models, Animal
 Lung Neoplasms Antibodies  >2 publications with PLXND1 and Lung Neoplasms
 Inflammation Antibodies  >2 publications with PLXND1 and Inflammation
 Brain Diseases Antibodies  >2 publications with PLXND1 and Brain Diseases
 Anxiety Disorders Antibodies  >1 publications with PLXND1 and Anxiety Disorders
 Weight Gain Antibodies  >1 publications with PLXND1 and Weight Gain
 Epilepsy Antibodies  >1 publications with PLXND1 and Epilepsy
 Nerve Degeneration Antibodies  >1 publications with PLXND1 and Nerve Degeneration

Organs/Tissues associated with anti-PLXND1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >36 publications with PLXND1 and Nerve
 Vascular Antibodies  >31 publications with PLXND1 and Vascular
 Blood Antibodies  >20 publications with PLXND1 and Blood
 Embryonic Tissue Antibodies  >17 publications with PLXND1 and Embryonic Tissue
 Brain Antibodies  >13 publications with PLXND1 and Brain
 Heart Antibodies  >6 publications with PLXND1 and Heart
 Muscle Antibodies  >5 publications with PLXND1 and Muscle
 Lung Antibodies  >4 publications with PLXND1 and Lung
 Bone Antibodies  >4 publications with PLXND1 and Bone
 Ganglia Antibodies  >4 publications with PLXND1 and Ganglia
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