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SPINK1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205324

SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in… More details

$245 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SPINK1, Recombinant Protein
Full Product Name
SPINK1, 24-79aa, Human, His tag, E Coli
Product Synonym Names
Serine peptidase inhibitor Kazal type 1; Serine peptidase inhibitor; Kazal type 1; PCTT; PSTI; Spink3; TATI; TCP
Sequence
MGSSHHHHHH SSGLVPRGSH MGSDSLGREA KCYNELNGCT KIYDPVCGTD GNTYPNECVL CFENRKRQTS ILIQKSGPC
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.5 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
8.6 kDa (79aa), confirmed by MALDI-TOF
3D Structure
ModBase 3D Structure for P00995
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for SPINK1 recombinant protein

Applications Tested/Suitable for SPINK1 recombinant protein
SDS-PAGE

Product References and Citations for SPINK1 recombinant protein

Witt H., et al. (2000) Nat. Genet. 25:213-216; Hassan Z., et al. (2002) Am. J. Hum. Genet. 71:964-968;

Other Notes

Small volumes of SPINK1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SPINK1 purchase

MBS205324 is a recombinant protein targeting SPINK1. Also known as SPINK1, 24-79aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SPINK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine protease inhibitor Kazal-type 1
NCBI Official Synonym Full Names
serine peptidase inhibitor, Kazal type 1
NCBI Official Symbol
SPINK1
NCBI Official Synonym Symbols
TCP; PCTT; PSTI; TATI; Spink3
UniProt Protein Name
Serine protease inhibitor Kazal-type 1
UniProt Synonym Protein Names
Pancreatic secretory trypsin inhibitor
UniProt Gene Name
SPINK1
UniProt Synonym Gene Names
PSTI; TATI
NCBI Protein Information
serine protease inhibitor Kazal-type 1

NCBI Summary for SPINK1

The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]
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UniProt Comments for SPINK1

Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:7142173). In the pancreas, protects against trypsin-catalyzed premature activation of zymogens ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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