ATP1B3 Recombinant Protein

Name: ATP1B3 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205557
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205557

ATP1B3 belongs to the X (+)/potassium ATPases subunit beta family. This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ATP1B3, Recombinant Protein

Full Product Name

ATP1B3, 57- 279aa, Human, His tag, E Coli

Product Gene Name

ATP1B3 recombinant protein

Product Synonym Names

sodium/potassium-transporting ATPase subunit beta-3; ATPB-3; CD298

Sequence

MGSSHHHHHH SSGLVPRGSH MGSTMWVMLQ TLNDEVPKYR DQIPSPGLMV FPKPVTALEY TFSRSDPTSY AGYIEDLKKF LKPYTLEEQK NLTVCPDGAL FEQKGPVYVA CQFPISLLQA CSGMNDPDFG YSQGNPCILV KMNRIIGLKP EGVPRIDCVS KNEDIPNVAV YPHNGMIDLK YFPYYGKKLH VGYLQPLVAV QVSFAPNNTG KEVTVECKID GSANLKSQDD RDKFLGRVMF KITARA

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.15M NaCl, 1mM DTT

Purity/Purification

> 80% by SDS-PAGE

Concentration

0.25mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

27.4 kDa (246aa) confirmed by MALDI-TOF

OMIM

U51478 mRNA

3D Structure

ModBase 3D Structure for P54709

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for ATP1B3 recombinant protein

Metabolism

Applications Tested/Suitable for ATP1B3 recombinant protein

SDS-PAGE

Product References and Citations for ATP1B3 recombinant protein

Malik N., et al (1998). Mamm. Genome 9:136-143; Chi A., et al (2006). J. Proteome Res. 5:3135-3144;

Other Notes

Small volumes of ATP1B3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATP1B3 purchase

MBS205557 is a recombinant protein targeting ATP1B3. Also known as ATP1B3, 57- 279aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP1B3. It may not necessarily be applicable to this product.

NCBI GI #

4502281

NCBI GeneID

483

NCBI Accession #

NP_001670

UniProt Primary Accession #

P54709

UniProt Secondary Accession #

B7Z1N7

UniProt Related Accession #

P54709

GenBank Nucleotide #

NM_001679.3

NCBI Official Full Name

sodium/potassium-transporting ATPase subunit beta-3

NCBI Official Synonym Full Names

ATPase Na+/K+ transporting subunit beta 3

NCBI Official Symbol

ATP1B3

NCBI Official Synonym Symbols

CD298; ATPB-3

UniProt Protein Name

Sodium/potassium-transporting ATPase subunit beta-3

UniProt Synonym Protein Names

Sodium/potassium-dependent ATPase subunit beta-3; ATPB-3; CD_antigen: CD298

UniProt Gene Name

ATP1B3

UniProt Synonym Gene Names

ATPB-3

NCBI Protein Information

sodium/potassium-transporting ATPase subunit beta-3

NCBI Summary for ATP1B3

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]

UniProt Comments for ATP1B3

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-3 subunit is not known.

Research Articles on ATP1B3

1. Our study demonstrated that ATP1B3 inhibit EV71 replication by enhancing the production of type-I interferons, which could act as a potential therapeutic target in EV71 infection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ATP1B3 recombinant protein

Reference Product	PubMed Publications
ATP1A1 recombinant protein	>7 publications with ATP1B3 and ATP1A1
ATP1B1 recombinant protein	>5 publications with ATP1B3 and ATP1B1
ATP1A3 recombinant protein	>4 publications with ATP1B3 and ATP1A3
ATP1B2 recombinant protein	>3 publications with ATP1B3 and ATP1B2
ATP1A2 recombinant protein	>3 publications with ATP1B3 and ATP1A2

Pathways associated with ATP1B3 recombinant protein

Products by Pathway	Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Aldosterone-regulated Sodium Reabsorption Pathway antibodies	Aldosterone-regulated Sodium Reabsorption Pathway Diagram
Aldosterone-regulated Sodium Reabsorption Pathway antibodies	Aldosterone-regulated Sodium Reabsorption Pathway Diagram
Basigin Interactions Pathway antibodies	Basigin Interactions Pathway Diagram
Bile Secretion Pathway antibodies	Bile Secretion Pathway Diagram
Bile Secretion Pathway antibodies	Bile Secretion Pathway Diagram
Calcium Regulation In The Cardiac Cell Pathway antibodies	Calcium Regulation In The Cardiac Cell Pathway Diagram
Carbohydrate Digestion And Absorption Pathway antibodies	Carbohydrate Digestion And Absorption Pathway Diagram
Carbohydrate Digestion And Absorption Pathway antibodies	Carbohydrate Digestion And Absorption Pathway Diagram

Diseases associated with ATP1B3 recombinant protein

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>1 publications with ATP1B3 and Lung Neoplasms
Infertility, Male Antibodies	>1 publications with ATP1B3 and Infertility, Male
Kidney Diseases Antibodies	>1 publications with ATP1B3 and Kidney Diseases

Organs/Tissues associated with ATP1B3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>4 publications with ATP1B3 and Muscle
Kidney Antibodies	>3 publications with ATP1B3 and Kidney
Blood Antibodies	>3 publications with ATP1B3 and Blood
Bone Antibodies	>2 publications with ATP1B3 and Bone
Brain Antibodies	>2 publications with ATP1B3 and Brain
Eye Antibodies	>1 publications with ATP1B3 and Eye
Liver Antibodies	>1 publications with ATP1B3 and Liver
Heart Antibodies	>1 publications with ATP1B3 and Heart
Connective Tissue Antibodies	>1 publications with ATP1B3 and Connective Tissue
Lung Antibodies	>1 publications with ATP1B3 and Lung