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Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2055652
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MBS2055652 is an antibody targeting HBEGF. Also known as PE-Linked Polyclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF). Reactive in Human, Pig. Host: Rabbit. More details

$285 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF), Polyclonal Antibody
Full Product Name
PE-Linked Polyclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)
Product Gene Name
anti-HBEGF antibody
Product Synonym Names
HB-EGF; DTR; DTS; DTSF; HEGFL; Diphtheria Toxin Receptor; Proheparin-binding EGF-like growth factor; Diphtheria toxin receptor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Pig
Concentration
>=100ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: HBEGF (MBS2003118)
PE Conjugated Antibody: HBEGF (MBS2055652)
Matching Pairs
PE Conjugated Antibody: HBEGF (MBS2055652)
Immunogen: HBEGF (MBS2010267)
Molecular Weight
22,808 Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
HBEGF (Val21~Thr160)
Conjugation
PE
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2003118
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-HBEGF antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-HBEGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HBEGF. It may not necessarily be applicable to this product.

NCBI GI #
1236400
NCBI GeneID
15200
NCBI Accession #
AAC52617.1
UniProt Related Accession #
Q06186
NCBI Official Full Name
heparin-binding epidermal growth factor-like growth factor
NCBI Official Synonym Full Names
heparin-binding EGF-like growth factor
NCBI Official Symbol
Hbegf
NCBI Official Synonym Symbols
Dtr; Dts; Hegfl; AW047313
UniProt Protein Name
Proheparin-binding EGF-like growth factor
Protein Family
Proheparin-binding EGF-like growth factor
UniProt Gene Name
Hbegf
UniProt Synonym Gene Names
Dtr; Hegfl; HB-EGF; HBEGF
NCBI Protein Information
proheparin-binding EGF-like growth factor

UniProt Comments for HBEGF

HBEGF: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18 B2|18 19.46 cM

Cellular Component: cell surface; extracellular space; integral to plasma membrane

Molecular Function: epidermal growth factor receptor binding; growth factor activity; heparin binding

Biological Process: blastocyst growth; cell migration; epidermal growth factor receptor signaling pathway; negative regulation of elastin biosynthetic process; positive regulation of cell growth; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of keratinocyte migration; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of smooth muscle cell proliferation; regulation of heart contraction; wound healing, spreading of epidermal cells
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Research Articles on HBEGF

1. Pelvic irradiation increases versican expression in bladder and rectum.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HBEGF antibody

 Reference Product  PubMed Publications
 Egfr antibody  >19 publications with HBEGF and Egfr
 Nrg1 antibody  >2 publications with HBEGF and Nrg1
 Nrg2 antibody  >1 publications with HBEGF and Nrg2
 Erbb3 antibody  >1 publications with HBEGF and Erbb3
 Adam17 antibody  >1 publications with HBEGF and Adam17
 Erbb4 antibody  >1 publications with HBEGF and Erbb4

Pathways associated with anti-HBEGF antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 EGFR Transactivation By Gastrin Pathway antibodies  EGFR Transactivation By Gastrin Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram

Diseases associated with anti-HBEGF antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >10 publications with HBEGF and Cardiovascular Diseases
 Inflammation Antibodies  >7 publications with HBEGF and Inflammation
 Necrosis Antibodies  >7 publications with HBEGF and Necrosis
 Breast Neoplasms Antibodies  >6 publications with HBEGF and Breast Neoplasms
 Heart Diseases Antibodies  >5 publications with HBEGF and Heart Diseases
 Disease Models, Animal Antibodies  >5 publications with HBEGF and Disease Models, Animal
 Lung Diseases Antibodies  >4 publications with HBEGF and Lung Diseases
 Neoplasm Metastasis Antibodies  >3 publications with HBEGF and Neoplasm Metastasis
 Hypertrophy Antibodies  >3 publications with HBEGF and Hypertrophy
 Neoplasms, Experimental Antibodies  >3 publications with HBEGF and Neoplasms, Experimental

Organs/Tissues associated with anti-HBEGF antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >10 publications with HBEGF and Lung
 Muscle Antibodies  >10 publications with HBEGF and Muscle
 Bone Antibodies  >6 publications with HBEGF and Bone
 Skin Antibodies  >6 publications with HBEGF and Skin
 Embryonic Tissue Antibodies  >6 publications with HBEGF and Embryonic Tissue
 Brain Antibodies  >5 publications with HBEGF and Brain
 Heart Antibodies  >4 publications with HBEGF and Heart
 Prostate Antibodies  >2 publications with HBEGF and Prostate
 Eye Antibodies  >2 publications with HBEGF and Eye
 Pancreas Antibodies  >1 publications with HBEGF and Pancreas
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