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COA4 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205674

Cytochrome c oxidase assembly factor 4 homolog, mitochondrial, also known as COA4, is the last enzyme of the mitochondrial respiratory chain, is a very complicated process and requires the assistance of a large number of accessory factors. It is essential for… More details

$245 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
COA4, Recombinant Protein
Full Product Name
COA4, 1-87a Human, His tag, E Coli
Product Gene Name
Product Synonym Names
Cytochrome c oxidase assembly factor 4 homolog mitochondrial; Cytochrome c oxidase assembly factor 4 homolog; mitochondrial; CHCHD8; CMC3; E2IG2
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSTSVPQ GHTWTQRVKK DDEEEDPLDQ LISRSGCAAS HFAVQECMAQ HQDWRQCQPQ VQAFKDCMSE QQARRQEELQ RRQEQAGAHH
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
12.5 kDa (110aa) confirmed by MALDI-TOF
OMIM
AF242180 mRNA
3D Structure
ModBase 3D Structure for Q9NYJ1
Antigen Species
Human
Tag Information
His-tag
Applications Tested/Suitable for COA4 recombinant protein
SDS-PAGE

Product References and Citations for COA4 recombinant protein

Diaz F., et al. (2012) Hum Mol Genet. 1 (23): 5066-77.; Huigsloot M., et al. (2011) Am J Hum Genet. 8 (4): 488-93.

Other Notes

Small volumes of COA4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COA4 purchase

MBS205674 is a recombinant protein targeting COA4. Also known as COA4, 1-87a Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for COA4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytochrome c oxidase assembly factor 4 homolog, mitochondrial
NCBI Official Synonym Full Names
cytochrome c oxidase assembly factor 4 homolog
NCBI Official Symbol
COA4
NCBI Official Synonym Symbols
CMC3; E2IG2; CHCHD8
UniProt Protein Name
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial
UniProt Synonym Protein Names
Coiled-coil-helix-coiled-coil-helix domain-containing protein 8; E2-induced gene 2 protein
UniProt Gene Name
COA4
UniProt Synonym Gene Names
CHCHD8; E2IG2
NCBI Protein Information
cytochrome c oxidase assembly factor 4 homolog, mitochondrial

UniProt Comments for COA4

Putative COX assembly factor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with COA4 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with COA4 and Inflammation
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