GNB1 Recombinant Protein

Name: GNB1 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205716
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205716

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GNB1, Recombinant Protein

Full Product Name

GNB1, 1-340aa, Human, His tag, E Coli (Denatured)

Product Gene Name

GNB1 recombinant protein

Product Synonym Names

guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-1; guanine nucleotide binding protein (G protein); beta polypeptide 1

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSELDQL RQEAEQLKNQ IRDARKACAD ATLSQITNNI DPVGRIQMRT RRTLRGHLAK IYAMHWGTDS RLLVSASQDG KLIIWDSYTT NKVHAIPLRS SWVMTCAYAP SGNYVACGGL DNICSIYNLK TREGNVRVSR ELAGHTGYLS CCRFLDDNQI VTSSGDTTCA LWDIETGQQT TTFTGHTGDV MSLSLAPDTR LFVSGACDAS AKLWDVREGM CRQTFTGHES DINAICFFPN GNAFATGSDD ATCRLFDLRA DQELMTYSHD NIICGITSVS FSKSGRLLLA GYDDFNCNVW DALKADRAGV LAGHDNRVSC LGVTDDGMAV ATGSWDSFLK IWN

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Purity/Purification

> 85% by SDS-PAGE

Concentration

0.25 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

39.8kDa (363aa)

OMIM

X04526 mRNA

3D Structure

ModBase 3D Structure for P62873

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for GNB1 recombinant protein

Signal Transduction

Applications Tested/Suitable for GNB1 recombinant protein

SDS-PAGE

Application Notes for GNB1 recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for GNB1 recombinant protein

Bhatnagar,A, et al. (2013) PLoS ONE 8 (1), E52689 ; Lim,Y.P., et al. (2012) BMC Gastroenterol 12, 167;

Other Notes

Small volumes of GNB1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNB1 purchase

MBS205716 is a recombinant protein targeting GNB1. Also known as GNB1, 1-340aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GNB1. It may not necessarily be applicable to this product.

NCBI GI #

11321585

NCBI GeneID

2782

NCBI Accession #

NP_002065

UniProt Primary Accession #

P62873

UniProt Secondary Accession #

P04697; P04901; Q1RMY8; B1AJZ7

UniProt Related Accession #

P62873

GenBank Nucleotide #

NM_002074.4

NCBI Official Full Name

guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform 1

NCBI Official Synonym Full Names

G protein subunit beta 1

NCBI Official Symbol

GNB1

NCBI Official Synonym Symbols

MRD42

UniProt Protein Name

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

UniProt Synonym Protein Names

Transducin beta chain 1

UniProt Gene Name

GNB1

NCBI Protein Information

guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

NCBI Summary for GNB1

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

UniProt Comments for GNB1

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Research Articles on GNB1

1. Through analysis of the genomic and proteomic profiles of resistant cells, we identified an acquired mutation in the GNB1 gene, K89M, as the most likely cause of the resistance

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GNB1 recombinant protein

Reference Product	PubMed Publications
GNAT1 recombinant protein	>5 publications with GNB1 and GNAT1
GNG2 recombinant protein	>3 publications with GNB1 and GNG2
GNGT1 recombinant protein	>2 publications with GNB1 and GNGT1
GNAI2 recombinant protein	>2 publications with GNB1 and GNAI2
GNAI1 recombinant protein	>2 publications with GNB1 and GNAI1
GNG12 recombinant protein	>1 publications with GNB1 and GNG12
GNG13 recombinant protein	>1 publications with GNB1 and GNG13
GNAI3 recombinant protein	>1 publications with GNB1 and GNAI3

Pathways associated with GNB1 recombinant protein

Products by Pathway	Pathway Diagram
ADP Signalling Through P2Y Purinoceptor 1 Pathway antibodies	ADP Signalling Through P2Y Purinoceptor 1 Pathway Diagram
ADP Signalling Through P2Y Purinoceptor 12 Pathway antibodies	ADP Signalling Through P2Y Purinoceptor 12 Pathway Diagram
Activation Of G Protein Gated Potassium Channels Pathway antibodies	Activation Of G Protein Gated Potassium Channels Pathway Diagram
Activation Of GABAB Receptors Pathway antibodies	Activation Of GABAB Receptors Pathway Diagram
Activation Of Kainate Receptors Upon Glutamate Binding Pathway antibodies	Activation Of Kainate Receptors Upon Glutamate Binding Pathway Diagram
Activation Of The Phototransduction Cascade Pathway antibodies	Activation Of The Phototransduction Cascade Pathway Diagram
Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway antibodies	Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Apelin Signaling Pathway antibodies	Apelin Signaling Pathway Diagram

Diseases associated with GNB1 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>3 publications with GNB1 and Inflammation
Liver Diseases Antibodies	>2 publications with GNB1 and Liver Diseases
Pneumonia Antibodies	>1 publications with GNB1 and Pneumonia
Liver Neoplasms Antibodies	>1 publications with GNB1 and Liver Neoplasms
Learning Disorders Antibodies	>1 publications with GNB1 and Learning Disorders
Cell Transformation, Neoplastic Antibodies	>1 publications with GNB1 and Cell Transformation, Neoplastic
Hypertrophy Antibodies	>1 publications with GNB1 and Hypertrophy
Cardiovascular Diseases Antibodies	>1 publications with GNB1 and Cardiovascular Diseases
Myocardial Infarction Antibodies	>1 publications with GNB1 and Myocardial Infarction
Hepatitis Antibodies	>1 publications with GNB1 and Hepatitis

Organs/Tissues associated with GNB1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>14 publications with GNB1 and Brain
Eye Antibodies	>11 publications with GNB1 and Eye
Blood Antibodies	>8 publications with GNB1 and Blood
Muscle Antibodies	>7 publications with GNB1 and Muscle
Vascular Antibodies	>3 publications with GNB1 and Vascular
Bone Antibodies	>3 publications with GNB1 and Bone
Heart Antibodies	>3 publications with GNB1 and Heart
Ganglia Antibodies	>2 publications with GNB1 and Ganglia
Ovary Antibodies	>2 publications with GNB1 and Ovary
Kidney Antibodies	>1 publications with GNB1 and Kidney