3 ug by SDS-PAGE under reducing condition and visualized by coomasie blue stain

NRF2 Recombinant Protein

Name: NRF2 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205893
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205893

Nuclear factor (erythroid-derived 2)-like 2, also known as NRF2, is bZIP transcription factors that heterodimerize with Maf proteins to bind Mare sequences. The NRF proteins also bind the antioxidant response element (ARE) and are implicated in the regulation… More details

$230 / 0.004 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NRF2, Recombinant Protein

Full Product Name

NRF2, 1-605aa, Human, His tag, E Coli

Product Gene Name

NRF2 recombinant protein

Product Synonym Names

Nuclear factor (erythroid-derived 2)-like 2; Nuclear factor (erythroid-derived 2)-like 2; NFE2L2

Sequence

< MGSSHHHHHH SSGLVPRGSH > MMDLELPPPG LPSQQDMDLI DILWRQDIDL GVSREVFDFS QRRKEYELEK QKKLEKERQE QLQKEQEKAF FAQLQLDEET GEFLPIQPAQ HIQSETSGSA NYSQVAHIPK SDALYFDDCM QLLAQTFPFV DDNEVSSATF QSLVPDIPGH IESPVFIATN QAQSPETSVA QVAPVDLDGM QQDIEQVWEE LLSIPELQCL NIENDKLVET TMVPSPEAKL TEVDNYHFYS SIPSMEKEVG NCSPHFLNAF EDSFSSILST EDPNQLTVNS LNSDATVNTD FGDEFYSAFI AEPSISNSMP SPATLSHSLS ELLNGPIDVS DLSLCKAFNQ NHPESTAEFN DSDSGISLNT SPSVASPEHS VESSSYGDTL LGLSDSEVEE LDSAPGSVKQ NGPKTPVHSS GDMVQPLSPS QGQSTHVHDA QCENTPEKEL PVSPGHRKTP FTKDKHSSRL EAHLTRDELR AKALHIPFPV EKIINLPVVD FNEMMSKEQF NEAQLALIRD IRRRGKNKVA AQNCRKRKLE NIVELEQDLD HLKDEKEKLL KEKGENDKSL HLLKKQLSTL YLEVFSMLRD EDGKPYSPSE YSLQQTRDGN VFLVPKSKKP DVKKN

Host

E Coli

Form/Format

Liquid. In phosphate buffer saline (pH 7.4) containing 10% glycerol

Purity/Purification

> 85% by SDS-PAGE

Concentration

0.25 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 2 to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Molecular Weight

69.9kDa (625aa)

3D Structure

ModBase 3D Structure for Q16236

Tag Information

His-tag

Domain

1-605aa

Product Categories/Family for NRF2 recombinant protein

Epigenetics

Applications Tested/Suitable for NRF2 recombinant protein

SDS-PAGE

Product References and Citations for NRF2 recombinant protein

Huang H C., et al. (2000) Proc Natl Acad Sci uSA. 97: 12475-12480.; Tsai P Y., et al. (2012) Arthritis Rheum. 64: 232-242.;

Other Notes

Small volumes of NRF2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NRF2 purchase

MBS205893 is a recombinant protein targeting NRF2. Also known as NRF2, 1-605aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NRF2. It may not necessarily be applicable to this product.

NCBI GI #

21361440

NCBI GeneID

5866

NCBI Accession #

NP_006155.2

UniProt Primary Accession #

Q16236

UniProt Secondary Accession #

Q86V32; Q9P1Q8

UniProt Related Accession #

Q8TBN0

GenBank Nucleotide #

NM_013401.3

NCBI Official Full Name

guanine nucleotide exchange factor for Rab-3A isoform 1

NCBI Official Synonym Full Names

RAB3A interacting protein like 1

NCBI Official Symbol

RAB3IL1

NCBI Official Synonym Symbols

GRAB

UniProt Protein Name

Guanine nucleotide exchange factor for Rab-3A

UniProt Synonym Protein Names

Rab-3A-interacting-like protein 1; Rab3A-interacting-like protein 1; Rabin3-like 1

Protein Family

Kelch-like ECH-associated protein

UniProt Gene Name

RAB3IL1

UniProt Synonym Gene Names

Rab3A-interacting-like protein 1

NCBI Protein Information

guanine nucleotide exchange factor for Rab-3A

NCBI Summary for NRF2

This gene encodes a guanine nucleotide exchange factor for the ras-related protein Rab3A. The encoded protein binds Rab3a and the inositol hexakisphosphate kinase InsP6K1. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2012]

UniProt Comments for NRF2

Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B.

Research Articles on NRF2

1. Intermediates in the guanine nucleotide exchange reaction of Rab8 protein catalyzed by guanine nucleotide exchange factors Rabin8 and GRAB.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NRF2 recombinant protein

Reference Product	PubMed Publications
RAB8B recombinant protein	>1 publications with NRF2 and RAB8B
RAB8A recombinant protein	>1 publications with NRF2 and RAB8A

Pathways associated with NRF2 recombinant protein

Products by Pathway	Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
RAB GEFs Exchange GTP For GDP On RABs Pathway antibodies	RAB GEFs Exchange GTP For GDP On RABs Pathway Diagram
Vesicle-mediated Transport Pathway antibodies	Vesicle-mediated Transport Pathway Diagram