Rabbit Anti-GTF3A Polyclonal Antibody – Cat# MBS2073476

Knockout Validation: Lane 1: Wild-type Jurkat cell lysate; Lane 2: GTF3A knockout Jurkat cell lysate; Predicted MW: 41,39kd Observed MW: 44kd Primary Ab: 1ug/ml Rabbit Anti-Human GTF3A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047)

General Transcription Factor IIIA (GTF3A) Antibody – Rabbit Polyclonal

Name: GTF3A Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2073476
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2073476

MBS2073476 is an antibody targeting GTF3A. Also known as APC/CY7-Linked Polyclonal Antibody to General Transcription Factor IIIA (GTF3A). Reactive in Human. Host: Rabbit. More details

$445 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

General Transcription Factor IIIA (GTF3A), Polyclonal Antibody

Full Product Name

APC/CY7-Linked Polyclonal Antibody to General Transcription Factor IIIA (GTF3A)

Product Gene Name

anti-GTF3A antibody

Product Synonym Names

AP2; TFIIIA

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Concentration

>=100ug/ml (lot specific)

Matching Pairs

Unconjugated Antibody: GTF3A (MBS2034029)
APC-CY7 Conjugated Antibody: GTF3A (MBS2073476)

Matching Pairs

APC-CY7 Conjugated Antibody: GTF3A (MBS2073476)
Immunogen: GTF3A (MBS2034224)

Molecular Weight

38,779 Da

OMIM

D32257 mRNA

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Immunogen

GTF3A (Val71~Gly365)

Conjugation

APC-Cy7

Cross Reactivity

Human

Unconjugated Antibody

The unconjugated antibody version of this item is also available as catalog #MBS2034029

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-GTF3A antibody

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-GTF3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF3A. It may not necessarily be applicable to this product.

NCBI GI #

119628809

NCBI GeneID

2971

NCBI Accession #

EAX08404.1

UniProt Secondary Accession #

Q12963; Q13097; B7ZBK5

UniProt Related Accession #

Q92664

NCBI Official Full Name

general transcription factor IIIA, isoform CRA_a, partial

NCBI Official Synonym Full Names

general transcription factor IIIA

NCBI Official Symbol

GTF3A

NCBI Official Synonym Symbols

AP2; TFIIIA

UniProt Protein Name

Transcription factor IIIA

UniProt Gene Name

GTF3A

UniProt Synonym Gene Names

TFIIIA

NCBI Protein Information

transcription factor IIIA

NCBI Summary for GTF3A

The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]

UniProt Comments for GTF3A

GTF3A: Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein; Transcription initiation complex

Chromosomal Location of Human Ortholog: 13q12.2

Cellular Component: nucleoplasm; nucleus

Biological Process: rRNA transcription; transcription from RNA polymerase III promoter

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GTF3A antibody

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
IL4-mediated Signaling Events Pathway antibodies	IL4-mediated Signaling Events Pathway Diagram
RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies	RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies	RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
RNA Polymerase III Transcription Pathway antibodies	RNA Polymerase III Transcription Pathway Diagram
RNA Polymerase III Transcription Initiation Pathway antibodies	RNA Polymerase III Transcription Initiation Pathway Diagram
RNA Polymerase III Transcription Initiation From Type 1 Promoter Pathway antibodies	RNA Polymerase III Transcription Initiation From Type 1 Promoter Pathway Diagram

Diseases associated with anti-GTF3A antibody

Disease Name	Pubmed Publications
Neurobehavioral Manifestations Antibodies	>1 publications with GTF3A and Neurobehavioral Manifestations
Abnormalities, Multiple Antibodies	>1 publications with GTF3A and Abnormalities, Multiple
Congenital Abnormalities Antibodies	>1 publications with GTF3A and Congenital Abnormalities

Organs/Tissues associated with anti-GTF3A antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1 publications with GTF3A and Blood
Ovary Antibodies	>1 publications with GTF3A and Ovary
Connective Tissue Antibodies	>1 publications with GTF3A and Connective Tissue
Testis Antibodies	>1 publications with GTF3A and Testis