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Phospholipase A2, Group IVD (PLA2G4D) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2083913
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MBS2083913 is an antibody targeting PLA2G4D. Also known as HRP-Linked Polyclonal Antibody to Phospholipase A2, Group IVD (PLA2G4D). Reactive in Human. Host: Rabbit. More details

$270 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Phospholipase A2, Group IVD (PLA2G4D), Polyclonal Antibody
Full Product Name
HRP-Linked Polyclonal Antibody to Phospholipase A2, Group IVD (PLA2G4D)
Product Gene Name
anti-PLA2G4D antibody
Product Synonym Names
cPLA2delta; Cytosolic phospholipase A2 delta
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: PLA2G4D (MBS2032099)
HRP Conjugated Antibody: PLA2G4D (MBS2083913)
Matching Pairs
HRP Conjugated Antibody: PLA2G4D (MBS2083913)
Immunogen: PLA2G4D (MBS2032985)
Molecular Weight
80,930 Da
OMIM
AB090876 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
PLA2G4D (Pro9~Leu120)
Conjugation
HRP
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2032099
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PLA2G4D antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-PLA2G4D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLA2G4D. It may not necessarily be applicable to this product.

NCBI GI #
119612935
NCBI GeneID
283748
NCBI Accession #
EAW92529.1
UniProt Secondary Accession #
Q8N176
UniProt Related Accession #
Q86XP0
NCBI Official Full Name
phospholipase A2, group IVD (cytosolic), isoform CRA_a
NCBI Official Synonym Full Names
phospholipase A2 group IVD
NCBI Official Symbol
PLA2G4D
NCBI Official Synonym Symbols
cPLA2delta
UniProt Protein Name
Cytosolic phospholipase A2 delta
UniProt Synonym Protein Names
Phospholipase A2 group IVD
Protein Family
Cytosolic phospholipase
UniProt Gene Name
PLA2G4D
UniProt Synonym Gene Names
cPLA2-delta
NCBI Protein Information
cytosolic phospholipase A2 delta

NCBI Summary for PLA2G4D

The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 [PubMed 14709560]).[supplied by OMIM, Jun 2009]

UniProt Comments for PLA2G4D

PLA2G4D: a calcium-dependent phospholipase A2 that catalyzes the release of arachidonic acid from membrane phospholipids. Selectively hydrolyzes glycerophospholipids in the sn-2 position. Not arachidonic acid-specific but has linoleic acid-specific activity. May play a role in inflammation in psoriatic lesions. Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in other tissues. Strongly expressed in the upper spinous layer of the psoriatic epidermis, expressed weakly and discontinuously in atopic dermatitis and mycosis fungoides, and not detected in the epidermis of normal skin. The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca2+. Two isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.1.4; Lipid Metabolism - arachidonic acid; Phospholipase

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: cytosol

Molecular Function: lysophospholipase activity; phospholipase A1 activity; phospholipase A2 activity

Biological Process: phosphatidic acid biosynthetic process; phospholipid metabolic process
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Research Articles on PLA2G4D

1. study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP, CBFA2T3, AMOTL1, FAT4, FBXO11, PLA2G4D, TRRAP and USH2A.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PLA2G4D antibody

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 Acyl Chain Remodelling Of PI Pathway antibodies  Acyl Chain Remodelling Of PI Pathway Diagram
 Acyl Chain Remodelling Of PS Pathway antibodies  Acyl Chain Remodelling Of PS Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
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