Rabbit Anti-PAG1 Polyclonal Antibody – Cat# MBS2096221

Phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) Antibody – Rabbit Polyclonal

Name: PAG1 Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2096221
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2096221

MBS2096221 is an antibody targeting PAG1. Also known as Biotin-Linked Polyclonal Antibody to Phosphoprotein Associated With Glycosphingolipid Microdomains 1 (PAG1). Reactive in Mouse. Host: Rabbit. More details

$230 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Phosphoprotein Associated With Glycosphingolipid Microdomains 1 (PAG1), Polyclonal Antibody

Full Product Name

Biotin-Linked Polyclonal Antibody to Phosphoprotein Associated With Glycosphingolipid Microdomains 1 (PAG1)

Product Gene Name

anti-PAG1 antibody

Product Synonym Names

CBP; PAG; Csk-Binding Protein; Transmembrane adapter protein PAG; Transmembrane phosphoprotein Cbp

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Mouse

Concentration

500ug/ml (lot specific)

Matching Pairs

Unconjugated Antibody: PAG1 (MBS2026130)
Biotin Conjugated Antibody: PAG1 (MBS2096221)

Matching Pairs

Biotin Conjugated Antibody: PAG1 (MBS2096221)
Immunogen: PAG1 (MBS2030092)

Molecular Weight

46,981 Da

OMIM

AF240634 mRNA

3D Structure

ModBase 3D Structure for Q9NWQ8

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Conjugation

Biotin

Cross Reactivity

Mouse

Immunogen

PAG1 (Gly160~Gln390)

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-PAG1 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-PAG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PAG1. It may not necessarily be applicable to this product.

NCBI GI #

63054864

NCBI GeneID

55824

NCBI Accession #

NP_060910.3

UniProt Primary Accession #

Q9NWQ8

UniProt Secondary Accession #

Q2M1Z9; Q5BKU4; Q9NYK0; A8K1A3

UniProt Related Accession #

Q9NWQ8

GenBank Nucleotide #

NM_018440.3

NCBI Official Full Name

phosphoprotein associated with glycosphingolipid-enriched microdomains 1

NCBI Official Synonym Full Names

phosphoprotein membrane anchor with glycosphingolipid microdomains 1

NCBI Official Symbol

PAG1

NCBI Official Synonym Symbols

CBP; PAG

UniProt Protein Name

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

UniProt Synonym Protein Names

Csk-binding protein; Transmembrane adapter protein PAG; Transmembrane phosphoprotein Cbp

Protein Family

Phosphoprotein associated with glycosphingolipid-enriched microdomains

UniProt Gene Name

PAG1

UniProt Synonym Gene Names

CBP; PAG

NCBI Protein Information

phosphoprotein associated with glycosphingolipid-enriched microdomains 1

NCBI Summary for PAG1

The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation. [provided by RefSeq, Jul 2008]

UniProt Comments for PAG1

PAG: an ubiquitous type III transmembrane adaptor protein that binds to the tyrosine kinase CSK protein. It is thought to be involved in the regulation of T cell activation.

Protein type: Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q21.13

Cellular Component: integral component of plasma membrane; intracellular; membrane raft; plasma membrane

Molecular Function: protein binding; SH2 domain binding; SH3/SH2 adaptor activity; transmembrane receptor protein tyrosine kinase adaptor protein activity

Biological Process: adaptive immune response; epidermal growth factor receptor signaling pathway; negative regulation of T cell activation; positive regulation of signal transduction; regulation of T cell activation; signal transduction; T cell receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on PAG1

1. Our study highlights the underlying mechanism of cross interaction between ASCs and breast cancer cells, and indicates that PAG1/Cbp in breast cancer cell may modulate tumor progression and acquired chemoresistance in the ASCs-associated breast cancer microenvironment through Src and AKT/mTOR pathways.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PAG1 antibody

Reference Product	PubMed Publications
CSK antibody	>62 publications with PAG1 and CSK
FYN antibody	>22 publications with PAG1 and FYN
LYN antibody	>20 publications with PAG1 and LYN
LCK antibody	>8 publications with PAG1 and LCK
CD4 antibody	>6 publications with PAG1 and CD4
PTPRC antibody	>4 publications with PAG1 and PTPRC
EGF antibody	>1 publications with PAG1 and EGF
PTPN11 antibody	>1 publications with PAG1 and PTPN11

Pathways associated with anti-PAG1 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
BCR Signaling Pathway antibodies	BCR Signaling Pathway Diagram
CXCR4-mediated Signaling Events Pathway antibodies	CXCR4-mediated Signaling Events Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
GAB1 Signalosome Pathway antibodies	GAB1 Signalosome Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Phosphorylation Of CD3 And TCR Zeta Chains Pathway antibodies	Phosphorylation Of CD3 And TCR Zeta Chains Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By EGFR Pathway antibodies	Signaling By EGFR Pathway Diagram
Signaling By EGFR In Cancer Pathway antibodies	Signaling By EGFR In Cancer Pathway Diagram

Diseases associated with anti-PAG1 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>13 publications with PAG1 and Immune System Diseases
Inflammation Antibodies	>10 publications with PAG1 and Inflammation
Cell Transformation, Neoplastic Antibodies	>10 publications with PAG1 and Cell Transformation, Neoplastic
Disease Models, Animal Antibodies	>6 publications with PAG1 and Disease Models, Animal
Brain Diseases Antibodies	>5 publications with PAG1 and Brain Diseases
Nervous System Diseases Antibodies	>5 publications with PAG1 and Nervous System Diseases
Cardiovascular Diseases Antibodies	>4 publications with PAG1 and Cardiovascular Diseases
Neoplasms, Experimental Antibodies	>3 publications with PAG1 and Neoplasms, Experimental
Lung Diseases Antibodies	>3 publications with PAG1 and Lung Diseases
Respiratory Tract Diseases Antibodies	>3 publications with PAG1 and Respiratory Tract Diseases

Organs/Tissues associated with anti-PAG1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>37 publications with PAG1 and Blood
Brain Antibodies	>12 publications with PAG1 and Brain
Placenta Antibodies	>10 publications with PAG1 and Placenta
Nerve Antibodies	>6 publications with PAG1 and Nerve
Embryonic Tissue Antibodies	>6 publications with PAG1 and Embryonic Tissue
Lymph Node Antibodies	>6 publications with PAG1 and Lymph Node
Spleen Antibodies	>5 publications with PAG1 and Spleen
Lung Antibodies	>5 publications with PAG1 and Lung
Kidney Antibodies	>5 publications with PAG1 and Kidney
Bone Marrow Antibodies	>4 publications with PAG1 and Bone Marrow