Angiogenin (ANG) Antibody – Mouse Monoclonal

Monoclonal

IgM

MANG-1

Mouse

Human

S/N (Tissue Culture Supernatant - lyophilised)

IgG concentration 0.3 mg/ml (lot specific)

ANGIOGENIN
Mouse anti Human Angiogenin (MANG-1) is a monoclonal antibody specific for angiogenin, a potent angiogenesis inducing polypeptide of approximately 16.5kDa responsible for inducing vascularization in both normal and malignant tissues through activation of vascular endothelium and smooth muscle cells ant triggering a number of processes including Cell migration and proliferation (Reviewed in) Angiogenin, also known as ribonuclease 5 demonstrates tRNA specific ribonuclease activity, this in turn is regulated by binding to the ribonuclease inhibitor. Angiogenin exerts its vascular stimulation potential through binding to cytoplasmic actin on the surface of endothelial cells, followed by endocytosis and subsequent translocation to the nucleus

Mouse anti Angiogenin, clone MANG1 stains single cells on human tonsil sections and endothelial cells in human terminal placenta. MANG-1 also demonstrates intense staining on carcinoma cells and of endothelial cells in intratumoral vessels

Prior to reconstitution store at +4 degree C.
After reconstitution store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended.
Shelf Life: 12 months from date of reconstitution.

16,550 Da

Chromosome: 14; NC_000014.8 (21152336..21162345). Location: 14q11.1-q11.2

105850

ModBase 3D Structure for P03950

Recombinant human angiogenin

0.01% Thiomersal
1% Bovine Serum Albumin

500 ul sterile deionised water

Phosphate buffered saline